Alcaline ionized water, WELL-BEING & HEALTH!

ALKALINE WATER: THE SECRET TO VITALITY AND ENERGY

Drink yourself healthy. Make the switch to alkaline water.

Our bodies are 75% water, making the quality of our drinking water the key to our health—and the pH of our drinking water the key to our vitality.

You can live that healthy, energetic lifestyle you’ve always dreamed of. Whether you want to keep up with your kids, grandkids, or just enjoy more pain-free days, help prevent generative disease including cancer,  we can help.

In short, here is what our PURE(FREE from ALL contaminants but with healthy minerals)  & alkaline ionized  water can do for you:

  • Cleans & detoxifies your body (but does NOT deplete if from healthy minerals as purified. distilled  & Reverse Osmosis water  )while delivering a powerful antioxidant( knows as – ORP,  that fights oxydative stress  by identifying and neutralizing free radicals in the body (  responsible damaging healthy cells DNA,   illness and premature aging ) .
  • Prevents most common illnesses.
  • Increase alkalinity/oxygen levels thus helps with degenerative disease caused by acidosis such as CANCER ,  HEART DISEASE , LIVER DISEASE, KIDNEY DISEASE and MANY OTHERS.
  • Increases your vitality and energy levels as well as reducing your biological age.
  • Antiaging effects and keeping skin young
  • Alkaline water can provide hydration by up to six times higher than any other type of water
  • Improves the effectiveness of the nutrition from your food, supplements and medicines.
  • MUCH MORE- read below

Here is why:

Did you know that an overabundance of acidity(acidosis) in the cells( in the body) could cause or worsen a degenerative disease including cancer & heart disease?

Acidity (as opposed to alkaline) means low pH (pH <7) and is closely related to  low oxygen levels .The term pH refers to concentration of the Hydrogen proton. Or, some will claim percentage of Hydrogen. There are other definitions including acid/alkaline balance. In general chemistry, acidic compounds tend to expel oxygen, while alkaline or base compounds (opposite of acid) absorb oxygen. A glass of vinegar and water will not absorb oxygen from the air, whilea glass of baking soda in water tends to do that. So, pH puts a number on the degree of acidity.Our modern diet, rich in acid-forming processed foods, especially sugars and cereals, meats & animal products & others.Other factors also contribute to acidosis, such as stress, pollutants & others.Excessive acid conditions drive out oxygen from the cells (from the body).

Here is an example to understand HOW important alkalinity is: cancer, the disease that causes millions of deaths every year, and ,according to WHO, is now present 1 in 4 people and will shortly affect 1 in 3 (statistically speaking, this means, in every family (father, mother, child) one member will get cancer)

Dr. Otto Warburg received the Nobel prize in 1931 for the discovery that unlike all other cells in the human body, cancer cells do not breathe oxygen. Cancer cells are anaerobic, which means that they derive their energy without needing oxygen.

Otto Wartburg’s research revealed that when a cell is acidic & does not receive 60% of its normal oxygen needs, it goes to a mechanism of fermentation and uncontrolled increase.

http://www.nobelprize.org/nobel_prizes/medicine/laureates/1931

Many scientists have confirmed Dr. Otto Wartburg’s discovery, using various scientific methods and techniques(from  Gaston Naessens using the Dark-field microscope  to recent studies  ) : long-term lack of oxygen in cells is the key driver of cancer growth.

Read more click here

It turns out that cancer cells cannot survive in the presence of high levels of oxygen.

Oxygen/alkalinity is frequently called a cancer cell’s worst enemy, and a variety ways and means to increase the body’s oxygen content have been developed over the decades worldwide.

Many degenerative diseases of our time (including cancer & heart disease) respond to oxygen / alkaline therapy.

Sang Whang, in his book “Reverse Aging”

  “In general,   degenerative diseases are the result of the accumulation of acid waste in us.   When we are born, we have the highest concentration of alkaline substances   and also   body pH is the highest   Since that time, the normal process of life is to gradually acidify. This is why   these degenerative diseases do not occur when you are very young.  

“Rejuvenation” requires two distinct phases:   Chemical and physical

 The first step is to reduce the acidity of the body so as to eliminate acid waste in the blood and cellular fluids safely and easily.

  The second step is   to physically pull the old waste stored in the blood stream so that they can be discharged from the body. 

The methods of delivering oxygen into the body & raise alkalinity are too numerous to describe here.

Did you know one of the most powerful ways you can counteract the acidity/low oxygen levels in your body’s cells, most likely caused by stress and lifestyle choices, is to drink alkaline water?

It’s actually very simple. Our bodies are 75% water, making the quality of our drinking water the key to our health—and the PH of our drinking water the key to our vitality.

You can live that healthy, energetic lifestyle you’ve always dreamed of. Whether you want to keep up with your kids, grandkids, or just enjoy more pain-free days, help prevent generative disease including cancer,  we can help.

For more info and details about each specific illness and treatment, click on the HEALTH USAGE tab above.

A

 Anti-Aging effects and Younger Skin:

Acid ionized water is considered to be more beneficial to the skin than usual when you wash your face , because the skin is an acidic organ and acidic water reduces microorganisms ,  reduce fine lines and reduces the amount of bacteria that causes pimples .

Acne: depending on the type of acne , there are different ways of using ionized water to treat it. None of them will hurt , so if one way does not work try another way .

1 . Where boils, inflammation & infection ( irritation ) it is recommended to spray PURE highly acidic water  (pH 2.5 )  and let it dry . When the place is completely dry , apply a bandage soaked in alkaline ionized water , FREE from contaminants  for 5 minutes . This enables the body to neutralize the acids that cause acne. Dry the area and then spray with water PURE acidic water  ( beauty  water – 4.5 pH – 5.5 pH ) and let it dry . Repeat this process two times per day.

2 . Where inflammation or infection use PURE acidic water ( beauty water  – 4.5 pH – 5.5 pH ) . For best results drink at least 50 ml / kg body weight optimally ionized  alkaline water FREE from contaminants

Allergies – such as asthma and hay fever indicates a super/overactive immune system , consume 1 liter / day optimally ionized  alkaline water FREE from contaminants

Arthritis – drink big quantities of optimally ionized alkaline  water,FREE from contaminants

Athlete’s Foot – Foot bathing is recommended twice a day with PURE acidic water , HEATED  .

Asthma – 1 L / day optimally ionized alkaline  water,FREE from contaminants

 

B

Back pain (LINK ) – recommend applying a water compresses on the affected area with PURE acidic water for half an hour , five times a day. You can drink 150 ml of PURE(with no contaminants) acidic water  five times a day, half an hour before meals .

Baskets – drink 1 liter / day optimally ionized alkaline  water,FREE from contaminants

Bloodstream see letter  P

Burning in the stomach – drink 100 ml optimally ionized alkaline  water,FREE from contaminants

Bruises – wash wounds, beginning with PURE acidic water .After 5 minutes with PURE  alkaline water. Wounds should be covered with sterile gauze and washed with PURE alkaline water every 4 -6 hours until complete healing .

C

Canceralkaline Ionized water FREE from contaminants without restrictions.Some minerals also help in cancer. For more  see our remineralizer filter,

Chest pain / cold –  washed with PURE acidic water  for 10 minutes , then 5 minutes with PURe alkaline water

Cholesterol – drink plenty of optimally ionized alkaline  water,FREE from contaminants

Chronic fatigue – recommended ingesting PURE, optimally ionized  alkaline water s . Consumption of 1.5-2 liters of alkaline water daily and we will see an improvement in irritable bowel syndrome .


Circulatory problems and poor circulation
 -consumption of  PURE alkaline ionized water reduces the accumulation of acid wastes that clogs the arteries , improving circulation

Cold – drink PURE alkaline water 1l/day

Constipation – recommended intake of half a liter of optimally ionized alkaline  water,FREE from contaminants on an empty stomach  , especially in the morning , at least half an hour before meals .

Colitis – recommended before bedtime ingesting of 100 ml of PURE acidic water , heated to 37-40 Celsius . 20 in later  drink 100 ml of optimally ionized alkaline  water,FREE from contaminants, heated. repeat the same procedure for three days . Pain stops since day one.

Cough – recommended 100 ml of PURE  alkaline water,  four times a day, half an hour after meals for two days in a row .

Cuts and scrapes : When the skin has been affected is recommended to use PURE highly acidic water contaminants (pH 2.5 ) at least once a day. This helps the immune system to avoid the micro -organisms such as bacteria , viruses, etc., which can enter the body through damaged skin . Then apply on broken skin  beauty water – pH 4.5 – pH 5.5  for 3 minutes and let it dry . This helps close pores and removes pain.  For best results drink at least 50 ml / kg body weight per day PURE alkaline water .

 

D

Degenerative diseases – drink big quantities of optimally ionized  alkaline water FREE from contaminants

Depression – drink optimally ionized  alkaline water FREE from contaminants

Dermatitis and skin : Wash with PURe acidic water(beauty water – pH 4.5 – pH 5.5 ) after 10 min wash with  optimally ionized  alkaline water FREE from contaminants

Diarrhea – recommended intake of 200 ml of PURE acidic water .If no improvement within one hour , repeat the procedure .

Diabetes – recommend ingestion of optimally ionized  alkaline water FREE from contaminants , which they say can cure even the worst cases of diabetes. One patient commented : at first I was forced to take insulin at a level of 24 , but now the blood sugar level reached 100-110 so I do not need to insulin.All I did was to drink every day 6 – 8 liters of alkaline water. After short-term problem solving , adopt an alkaline lifestyle and you can reduce quantity of ingested water  .

 

E

Eczema : The best approach is the one used it for acne. Again , depending on the severity. We were successful in both cases , simply spraying acidic water with no contaminants (beauty water  – 4.5 pH – 5.5 pH ) of 3-6 times a day and allowing to dry . If someone has a more severe disease use highly acidic water with no contaminants (pH 2.5 ) and let it dry . When completely dry , apply a bandage soaked in PURE  strongly alkaline water  ( pH 11.5 ) on the area for 5 minutes. This allows the body to neutralizele acids that caused the disease . Dry the area and spray with  beauty water  – 4.5 pH – 5.5 pH  , let it dry . Repeat this procedure at least twice a day. It is recommended to spray  beauty  water for at least 2 hours. For best results drink at least 50 ml / kg body weight per day optimally ionized  alkaline water FREE from contaminants

Enlarged prostate – recommend ingesting 100 ml optimally ionized alkaline water without contaminants ,4 times a day, half an hour before meals , for 8-12 days.In many cases  large amounts of alkaline water without contaminants helps  when consumed on a daily basis at least one liter.

 

F

Fungi and Mushrooms – Wash affected areas twice daily , beginning with acidic water with no contaminants for 10 minutes , and after about five minutes with PURE alkaline ionized water Repeat the process for three weeks , even if the fungus disappear in time.

Flu and Cold – wash nasal passages eight times per day with PURE, acidic water and gargle for 10 minute.Evenings  before bed , drink 200 ml of alkaline ionized water ,PURE . Treatment for 2-3 days .

G

Gall stones-, drink plenty of PURE  alkaline water

Gout – this disease occurs due to accumulation of undissolved crystals of acids, especially uric acid in the joints and surrounding tissues .It is related to buildup of w acid aste ! Recommend the consumption of large amounts of optimally ionized  alkaline water FREE from contaminants

H

Hair loss –  wash the affected area twice daily , first with PURE acidic water and after about 5 minutes with PURE  alkaline water , for three weeks .

Hangovers – to neutralize alcohol ( producing strong acid salts ) and to balance the pH level is recommended ingestion of large quantities optimally ionized  alkaline water, FREE from contaminants.

Headache –  compresses with PURE acidic water

Heart problems – most heart disease is caused by the accumulation of waste acids. To improve heart condition it is recommended daily ingestion of a liter of alkaline ionized water FREE from contaminants .

Heartburn –  compresses with PURE, acidic water  for 10 minutes, then rinse with PURE alkaline waters ;  the blisters can be breaked with a sterile needle , then put a compress with PURE acidic water .  5-10 minutes later rinse with PURE alkaline water . baths with PURE  alkaline water is repeated every three hours untill healing. The affected area should be protected during treatment with sterile gauze

Haemorrhage – external wounds can be treated with acidic water,PURE to stop bleeding , while at the same time disinfect .PURE acidic water can be used for bleeding gums by rinsing mouth . After  you drink large amounts of PURE alkaline water bleeding gums will disappear completely .

Hemorrhoids – after emptying the bowels , wash the affected area with PURE acidic water.. Immediately after drying , apply a cotton ball soaked in PURe alkaline water. In case of internal hemorrhoids , apply a PURE acidic water enema ( 50-100 ml ) over 5 minutes, followed by PURE alkaline water enema  for half an hour . Early treatment is recommended ingestion of 150 ml of PURE acidic water on an empty stomach , followed two hours later by ingestion of 250 ml of PURE alkaline water . Continuing with alkaline water with no contaminants . every 4 hours , each time half an hour before meals .

Herpes – wash the affected area twice daily, beginning with PURE acidic water for 10 minutes and then after about 5 minutes with alkaline water, PURE( with no contaminants) . Treatment will last three weeks.

Hypertension – regularly drinking our best optimally alkaline ionized water ,without contaminants leads in time to normalize blood . Calcium (ionized) in  alkaline water is beneficial to the heart and thus to regulate blood pressure.

 

I

Immune system problems– drink 1 liter / day PURE, optimally alkaline ionized water- raises blood oxygen level and is good protection against contagious diseases and fortifies & maintains sytong immune system .Recommended daily intake of 30 ml of PURE,  alkaline water / pound. At a weight of 80 kg is recommended to consume 2.4 liters of PURE , alkaline water .

Inflammation and infection : wash with PURE acidic water , then make compress with PURE alkaline water ;
Inflammation of the liver – the first day drink 300 ml of acidic water with no contaminants , five times a day, half an hour before meal.In next 3-4 days drink 300 ml of alkaline water FREE from  contaminants five times a day, half an hour before meals .

Inflammation / infection of the vagina : wash with PURE acidic water  , after which with PURE( without contaminants ) alkaline water;

 

J

Joint pain : drink 100 g of  PURE acidci water for two days , 3 times / day ;

 

K

Kidney disease – drink plenty of optimally ionized  alkaline water FREE from contaminants

Kidney stones – kidney stones are formed of calcium, phosphoric acid and uric acid . Calcium but it is only binding element within the stones necessary to minimize the effects of phosphoric and uric acids . Ingesting PURE alkaline water helps to dissolve acid wastes and calcium release .

Kidney Problems – after neutralization of wastes from the blood by alkaline water without contaminants , the kidneys are forced to filter toxines.  Consuming more PURE optimally alkaline water , the more dilute acids in the blood will be and the easier for kidneys to remove wastes.

 

L
Laryngitis – gargle 5 times / day with PURE acidic water

Leg ulcers – wash affected areas with PURE acidic water , followed by application of PURE alkaline water compresses .Repeat application compresses every 4 hours. Areas must be wrapped in sterile packs . It is important during treatment to spend time lying down .

 

M

Migraine : see headache and consume PURE alkaline water

Moles , warts, etc. : If you have skin abnormalities using PURE, strongly acidic water ( pH 2.5) is likely to see results. In most cases it is easier to use a bandage soaked in water for taping this area. Change the bandage at least once a day . Most people have noticed that had to continue the procedure described above , from 30 to 60 days to see results. If moles , warts are in an area that presents difficulties in applying the bandage during the day or in public , apply bandage in your leisure time.

Morning sickness drink alkaline water without contaminants ;

Mouth wash : Use PURE .  strongly acidic water (pH 2.5 ) to gargle . This water kills bacteria and other micro -organisms in less than a minute. Bacteria in the mouth leading to the production of cavities.

Muscle pain after exercise – recommended intake of alkaline water, FREE from  contaminants to help neutralize lactic acid

 

O

Obesity – increased stomach in men and women  show an accumulation of acid waste products in the blood . Blood circulation in these areas is very low , which explains why people in dieting lose weight everywhere they do not want  . PURE, optimally ionized  alkaline water neutralizes these acid wastes .Process is slow but absolutely sure.In same time minimizes the feeling of hunger  recommend minimum 1.5 liters daily.

Osteoporosis – calcium is pulled out of the bones to balance  increasing acidity the body accumulates in time . By losing calcium bones become fragile and we become ill from osteoporosis . To counteract this process is recommended ingestion of large amounts of PURE(yet remineralized), alkaline water .

 

P

Psoriasis : See the Eczema

 

R

S.

Sore throat – gargle with  PURE, strongly acidic water  (pH 2.5 ) for 3 to 4 times daily

If you have a child who can not gargle put water in a spray bottle and spray for 3-4 times a day ( it will not hurt them if they swallow water). Most times children tell us that their pain goes away in a few minutes.

Skin Mushrooms/Fungus – wash skin with  PURE acidic water , then 5 minutes with PURE alkaline water

Sleepiness – frequently happens in the afternoon as people feel tired Why? After eating , the stomach needs a lot hydrochloric acid to digest food. It may not be stored , so blood must produce it in a very short span of time. Therefore , ingestion of PURE alkaline ionized water  . half an hour before and after each meal is very beneficial.

Sunburn : If sunburn is not severe enough for medical intervention , apply , strongly alkaline  water FREE from contaminants ( pH 11.5 ) on the skin , or a bandage soaked in the water. When you finish the procedure applying PURE  acidic water (beauty water – 4.5 pH – 5.5 pH ) . over the entire area and let it air dry before covering the area with clothing. If you can repeat the operation . For best results drink at least 50 ml / kg body weight per day optimally   ionized alkaline water FREE from  contaminants

 

T
Tonsillitis
 – gargle for 5 times / day with PURE( FREE from contaminants)  acidic water

Toothache – rinse the mouth with PURE acidic water

 

W

Wounds/ Bruises – wash wounds, beginning with PURE acidic water .After 5 minutes with PURE  alkaline water. Wounds should be covered with sterile gauze and washed with PURE alkaline water every 4 -6 hours until complete healing .

Water retention : drink PURE alkaline water ;

 

DISEASES AND  RECOMMENDED  USE , INFORMATIONAL PURPOSE ONLY  Does NOT  replace MEDICAL TREATMENT

DO NOT TAKE DRUGS with alkaline water as it can effect being absorbed more quickly

It is important to know the symptoms of acidosis because these are what alkaline water neutralizes.

Symptoms of Acidosis

Alkaline Water Benefits

Headaches Fewer occurrences of headaches
Sleepiness / Fatigue Increased energy
Confusion Clear thinking
Shortness of breath Easy respiration
Coughing / Mucus Less throat irritation / Less mucus
Heart Arrhythmia Healthy heart function
Increased heart rate Healthy heart function
Nausea Fewer occurrences of ‘feeling sick’
Diarrhea More stable and regular bowel movements
Increased likelihood of developing chronic disease Decreased likelihood of developing chronic disease

Are there any other alkaline water & PURE benefits?

Alkaline water helps to neutralize acids and remove toxins from the body. Alkaline water also acts as a conductor of electrochemical activity from cell to cell. Other alkaline water benefits include:

  • Increased intracellular hydration
  • Decreased likelihood of developing acidosis
  • Constant replenishment of essential minerals for pH balancing
  • Increased ability of cells to expel wastes

Alkaline water restores the body’s pH balance

Do you often feel tired or lethargic? Do you suffer from frequent colds, infections, illnesses, or joint pain?  Do your nails, skin, and hair look and feel unhealthy? If so, then your body may be too acidic!

What you eat, drink, put on your skin, the quality of the air you breathe, the exercise you do and even the thoughts you think can all contribute to make your body acidic. Most people are too acidic, and that drains their energy and causes illness and disease without them realising that’s the cause.

Note: acidic simply means their cellular pH is lower than 7. It is important to know that our bodies function properly /optimally when our cells are slightly alkaline(pH >7)

 

Alkaline water acts as a powerful antioxidant

Alkaline ionized water is a strong source of anti-oxidants since it contains an abundance of free electrons which can be donated to the body in order to neutralize free radicals.

But what exactly is oxidation? Think of what happens to a slice of apple left out on the counter for a few hours: it turns brown due to exposure to unstable oxygen molecules in the air.  Inside our bodies, our cells are also continuously subjected to oxidation due to the presence of oxygen free radicals, which are unstable molecules desperately seeking electrons for stability.  Free radicals have been scientifically proven to cause cellular and DNA damage that contribute to aging and can lead to the onset of various diseases.

 

Alkaline water super-hydrates the body

Water molecules come in clusters rather than single molecules. Tap water which is under pressure has very large clusters of 12-16 molecules. The ionization process breaks the electrical bonding of water molecules and restructures the water down to about 5-8 molecules per cluster. This smaller cluster size means that the water can be more easily absorbed into the cells, thereby providing superior hydration for the body and helping to dissolve and flush out acidic solid waste and toxins that have accumulated in the body.

Because of its ability to hydrate the body and flush out toxins, our FREE from contaminants & alkaline water  helps the body first by eliminating the toxins, second by restoring cellular pH to alkaline ( provides the body with alkaline minerals to help buffer acidity and build acid buffering reserves) , and also offers a powerful antioxidant( – ORP ) to bond to free radicals and prevent cellular DNA  damage and aging.

Regular surveys of PURE(FREE fom contaminats ONLY), alkaline water drinkers have revealed a number of dramatic benefits.

All testimonials have been verified as 100% authentic by TestimonialShield.com:

  • Weight Loss
  • Stabilized blood sugar
  • Reduced allergy symptoms and headaches
  • Increased circulation and blood oxygen levels
  • Increased energy
  • Improved immune function – less frequent colds and flush
  • Eases stomach aches and intestinal discomfort
  • Aids digestion
  • Aids in detoxification
  • Improved arthritis – decreased joint pain
  • Natural diuretic
  • More youthful skin appearance
  • Excellent hydration
  • No bloating when drinking large quantities
  • Improved mental clarity and a sense of well-being
  • Reduced stress
  • Pets refuse to drink anything but alkaline water
  • Best tasting water ever!
  • Helps stop the spread of cancer

 

But don’t take our word for it.

See what professionals and consumers have to say about the life-changing benefits of alkaline water by filling out the form, then checking your email for details on your FREE DVD.

As an added bonus you can request a free consultation with one of our water specialists, who can help you get a free analysis of your municipal tap water.

[contact-form subject=’Testimonials DVD’][contact-field label=’Email’ type=’email’ required=’1’/][contact-field label=’Comments’ type=’textarea’/][/contact-form]
 

Our  water ionizers are certified medical devices ,are approved by Korea FDA and  by Japanese Health Ministry 

Our  water ionizers approved by multiple countries’ Health Departments 

OUR water ionizers have been ENDORSED by New York Best Selling Authors, Dr. Robert O. Young, author of “The pH Miracle”, and Dr. Ben Johnson author of “The Healing Codes”.

Also, OUR water ionizers are the choice for Dr. Ted Baroody, notable author of “Alkalize or Die” and Sang Whang, scientist and author of, “Reverse Aging”.

OUR products have been chosen for a variety of ionized water applications by professional athletes, physicians, embassies, health practitioners, hospitals, commercial companies, horticulturists, executive chefs, alternative health centers, and more.

OUR water ionizers, NOT Kangen Enagic or other brands!

In the end , we would like to inform you ,that while it is true that on the short term , STRONGLY ionized ( alcaline or acidic ) water has it;s usage and benefits, on the long term : Balance Is Key

Experts do NOT recommend drinking water over pH 9.5 -such as Dr. Theodore Baroody (author Alkalize or Die), Dr. Robert O. Young (The pH Miracle), Sang Wang (Reverse Aging) and the Korean FDA plus Japanese Ministry of Health.

 

We will quote Dr Mercola:

As is true with many things, in the end it’s a matter of balance. Water that is too acidic or too alkaline used over  a long period can be detrimental to human health and lead to nutritional disequilibrium . This was demonstrated in a Swedish well water study [1], which found both pH extremes to be problematic. Your body simply was NOT designed to drink highly alkaline water ALL the time.

It makes sense that you are designed to drink water that occurs naturally, which excludes alkaline water with pH levels of 8 and above.

Living Water

What you want is pure water – water that is clean, balanced, and healthful, neither too alkaline nor too acidic. Ideally, the pH of your water should be somewhere between 6 and 8.

Thus, OUR water ionizers offer you BOTH PURE (FREE from ALL known water contaminants , but NOT from healthy minerals as opposed to dangerous distilled & purified(i.e: Reverse Osmosis ) water  ) & OPTIMALLY IONIZED water- HEALTHY water

– with the BEST possible water filtration from ALL known water contaminats with an outstanding precision of 99.9% , including chlorine, chloramines nitrates, BPA, fluoride , arsenic, etc), but WITH healthy, natural minerals to pass (we even remineralize water)(as opposed to dangerous distilled & purified water (i.e.Reverse Osmosis) our water is a fountain of HEALTH, detoxifying your body without depleting it from essential minerals

-as opposed to other brands that focus on producing wide range of pH & ORP, though ALL our water ionizers can and will produce ionized water with wide range of pH & ORP , ALL our water ionizers are designed to optimally ionize your water – with a unique history of over 30 years research and experience , collaborations with hospitals , medical centers, specialists and researchers,we think that what nature creates should be a reference point .

NATURALLY occurring alkaline and ionized water is NOT generally over pH 9 nor does it have artificially high – ORP. We know – we went to Vilcabamba, Ecuador to meet with the people in the Valley of Longevity and tested their water.

There are five locations in the world where scientists have found a type drinking water that exhibits extraordinary physical characteristics and where the inhabitants reportedly live to be over 100 years of age, are in excellent health, have no cancer, no dental caries, are robust and have children in their old age. They are called Hunzaland in the Karkorum Mountains just north of Pakistan in the Himalayas, the Vilcambamba in Ecuador, a high mountain valley in Georgia, Russia, another in Mongolia and the final one in Peru.  Though all these areas have different cultures and diets, they all have one thing in common – their water has similar properties.We studied them & tried our best to replicate them!

If interested, please ask for our FREE DVD on this trip contact us or leave your mail address( we will not share it with anyone)  [contact-form subject=’Valley DVD’][contact-field label=’Email’ type=’email’ required=’1’/][contact-field label=’Comments’ type=’textarea’/][/contact-form]

Featured on American Health Journal :

 

Although highly ionized water has its short term/immediate benefits in serious conditions ( emergency problem solving ) , long term well-being  & health is achieved and maintained  through balance along with an alkaline lifestyle( starting  with the way we think , love and enjoy life , the water we drink , foods we eat , how active we are , how much quality sleep we get & other factors ). Therefore, ALL AlkaViva water ionizers  are optimized to produce ionized water (alkaline & acidic) with optimal pH and ORP levels that you will enjoy and you will find the most beneficial and healthy as we found as a result of 30 years of experience in the field of natural health.

We also offer solutions to remineralize and rebalance water without using electricity/water ionization  for those who have water that is naturally low in minerals or for those who just want to enjoy water without contaminants , NOT ionized , but with beneficial minerals .

9.5 out of 10 alkaline water drinkers surveyed say they do NOT drink water that is over pH 9.5 – they do not enjoy the taste!

1 I Rosborg, et al. “Inorganic constituents of well water in one acid and one alkaline area of south Sweden,” (May 13, 2002) Lund University, Lund, Sweden Water; Air and Soil Pollution (2003) 142: 261-277

Sincerely, Cristian Gologan  & AlkaViva EU team , www.water-ionizers.info

For a FREE consultation with our alkaline water experts, CONTACT US :email, chat , phone

Disclaimer:

The information on this website is for information purposes only. It is not designed to diagnose, treat, cure or prevent any disease. It should not be construed as personal medical advice or instruction. No action should be taken based solely on the contents of this website. Readers should consult appropriate health professionals on any matter relating to their health and well-being. The information and opinions provided here ARE believed to be accurate and sound, based on the best judgment available to the authors, but readers who fail to consult appropriate health authorities assume the risk of any injuries.

The publisher is not responsible for errors or omissions.

Do NOT drink ionized water with a pH over 9.8.

Do NOT consume acid ionized water.

Some medications may be affected if taken with alkaline water. Take these medications with water from the “Purified” (neutral) setting.

Consult your physician. Water ionizers should not be used on water that is microbiologically unsafe without a proper water filter.

If you plan to use the water ionizer with well water that is very hard or high in iron or sulfur, please contact us first.

9 thoughts on “Alcaline ionized water, WELL-BEING & HEALTH!”

  1. Dr. William Donald Kelley, autorul cartii “ONE ASWER TO CANCER “:
    “Apa alcalina ionizata este cea mai mare realizare in domeniul sanatatii de la descoperirea penicilinei de catre doctorul Sir Alexander Fleming.”

    Dr. Don Colbert, M.D., autorul cartii “The Seven Pillars of Health” :
    “Cand bolnavii de cancer intra in cabinetul meu corpul lor este intotdeauna super acid si plin de toxine. Prima mea grija este sa le alcalinizez tesuturile cu apa alcalina ionizata. Din clipa cand au inceput sa urmeze dieta alcalina, consumand apa alcalina ionizata, urina acestora a devenit normala, nu au mai avut nici un fel de dureri, renuntand in cele din urma si la tratamentul cu medicamente.”

  2. Alkaline Water

    Clinical Documentary Reports from Doctors

    HIGH BLOOD PRESSURE

    Prof. Kuninaka Hironage, Head of Kuninaka Hospital
    For over 10 years of my experience, my concept towards minerals, especially pertaining to ioniccalcium in high blood pressure and other diseases is most significant.In accordance to the theory of medical Prof. Gato of Kyushu University on Vitamin K (because vitaminK enables the blood calcium to increase), or the consumption of more alkaline ionic water, theeffectiveness of the increase in calcium in high blood pressure is most significant. Most illnesses arecaused by too much fats in the diets, which lead to the deposition of cholesterol on the blood vesselswhich in turn constrict the blood flow. This results in high blood pressure.By drinking alkaline ionic water for a period of 2 to 3 months, the blood pressure should slowly drop,because the alkaline ionic water is a good solvent which dissolves the cholesterol in the blood vessels.

    HEART DISEASES

    Prof. Kuwata Keijiroo, Doctor of Medicines
    In my opinion, the wonder of alkaline ionic water is the ability to neutralise toxins, but it is not amedicine. The difference is that the medicine can only apply to each and individual case, whereas thealkaline ionic water can be consumed generally and its neutralising power is something which is verymuch unexpected. Now, in brief, let me introduce to you a heart disease case and how it was cured.The patient was a 35 years old male suffering from valvular heart disease. For 5 years, his sicknessdeteriorated. He was in the Setagays Government Hospital for treatment.During those 5 years, he had been in and out of the Hospital 5 to 6 times. He had undergone high techexaminations such as angiogram by injecting VINYL via the vein into the heart. He consulted andsought treatment from many good doctors where later he underwent a major surgical operation. Uponhis discharge from the hospital, he quit his job to convalesce. However, each time when his illnessrelapsed, the attack seemed to be even more severe. Last year, in August, his relatives were in despairand expected he would not live much longer. It so happened at that time that the victim’s relative cameacross the alkaline ionic water ionizer. His illness responded well and he is now on the road torecovery.

    KIDNEY DISEASES

    Prof. Kuwata Keijiroo, Doctor of Medicine
    The difference between drinking alkaline ionic water and the normal water is that the excretion of urineis slightly more than intake. However, for severe kidney failure patients, water intake has toberestricted.Consuming alkaline ionic water for these patients in controlled amounts proved to be beneficial.Normal tap water contains phosphate, calcium carbonate and the acidic ions. These acidic ions tend toreduce the efficiency of the calcium ions.Pure alkaline ionic water does not have these problems and it can effectively strengthen the heart andincrease urination. After consuming the alkaline ionic water for a month, the amount of urea and uricacid in the blood will show a marked improvement but will not disappear completely.However, if you continue to drink alkaline ionic water for a period of 6 to 12 months, the urea and uricacid should be grossly reduced. Intake of protein during this period should also be controlled, persistentdrinking of alkaline ionic water should eliminate the toxic effect of the urea and uric acid from thebody.According to a foreign paper report, patients undergoing dialysis tend to have their negative ionssignificantly reduced and the positive ions increased. Hence, according to the above experiment andfrom my personal clinical experience, drinking alkaline ionic water increases the positive ions whichwill have a significant effect on various kidney diseases. When kidney diseases do not respond tovarious drugs, it is good to threat them with alkaline ionic water.

    ECZEMA

    Prof. Tamura Tatsuji, Keifuku Rehabilitation Centre
    Eczema is used to describe several varieties of skin conditions which have a number of commonfeatures. The exact cause or causes of eczema are not fully understood. In many cases, eczema can beattributed to external irritants.Let me introduce a patient who recovered from skin disease after consuming the alkaline ionic water.This patient suffered 10 years of eczema and could be cured effectively even under specialist treatment.This patient, who is 70 years of age, is the President of a vehicle spare parts company. After the war,his lower limbs suffered acute eczema and later became chronic. He was repeatedly treated in aspecialist skin hospital.

    The left limb responded well to treatment, but not so on the right limb. He suffered severe itchiness,which, when scratched led to bleeding. During the last 10 years, he was seen and treated by manydoctors. When I first examined him, his lower limb around the joints was covered with vesicles.Weeping occurred owing to serum exuding from the vesicles.I advised him to try consuming alkaline ionic water. He bought a water ionize and consumed thealkaline ionic water religiously and used the acidic water to bathe the affected areas. After 2 weeks of treatment, the vesicles dried up. The eczema was completely cleared without any relapse after l ½ months.

    ALLERGY

    Prof. Kuninaka Hironaga, Head of Kuninaka Hospital

    Mr. Yamada, the head o Police Research Institute, suffered from severe allergy. He was treatedrepeatedly by skin specialist, but with no success. Then, he started consuming alkaline ionic water. Theallergy responded very well and was soon completely cured. No relapse had occurred, although he hadtaken all kinds of food. He was most grateful and excited about this treatment.As for myself, I had also suffered severe allergy. Ever since I began to consume alkaline ionic water,the allergy has recovered. Since then, I started a research on the effectiveness of alkaline ionic water. Idiscovered that most allergy is due to acidification of body condition and is also related to consumingtoo much meat and sugar. In every allergy case, the patient’s ionic calcium are excessively low whichin turn lower the body resistance significantly. The body becomes overly sensitive and develops allergyeasily. To stabilise the sensitivity, calcium solution is injected into the vein. Therefore, it is clear thatthe alkaline ionic water which has ionic calcium can help to alleviate allergy.The ionic calcium not only enhances the heart, urination, neutralization of toxins but controls acidity. Italso enhances the digestive system and liver function. This will promote natural healing power andhence increase its resistance to allergy. In some special cases of illness which do not respond to drugs,it is found to respond well to alkaline ionic water.

    DIGESTIVE SYSTEM PROBLEM

    Prof. Kogure Keizoo, Kogure Clinic of Juntendo Hospital

    The stomach is readily upset both by diseases affecting the stomach and by other general illnesses. Inaddition, any nervous tension or anxiety frequently causes gastric upset, vague symptoms when theyare under some strain.The important role of alkaline ionic water in our stomach is to neutralsie the secretion and strengthenits functions. Usually, after consuming the alkaline ionic water for 1 to 3 mins., the gastric juice

    increase to l l/2 times. For those suffering from hypochlorhydria or achlorhydria (low in gastric juice)the present of alkaline ionic water will stimulate the stomach cells to secrete more gastric juice. This inturn enhances digestion and absorption of minerals.However, on the other hand, those with hyperchlorhydria (high in gastric juice), the alkaline ionicwater neutralises the excessive gastric juice. Hence, it does not create any adverse reaction.According to the medical lecturer from Maeba University, the pH of the gastric secretion will stillremain normal when alkaline ionic water is consumed. This proved that the ability of the alkaline ionicwater is able to neutralise as well as to stimulate the secretion.Note: According to the Singapore Ministry of Health, Colo-rectal Cancer is 13% of cancer deaths.Colo-rectal cancer is one of the fastest-spreading cancer in Singapore and is fast overtaking lung canceras the leading cancer killer. Those in the high-risk group are Chinese and those above 45 years. One in25 Chinese has a possibility of being a victim — The Straits Times 18/7/1992

    DIABETES

    Prof. Kuwata Keijiroo, Doctor of Medicine

    When I was serving in the Fire Insurance Assocation, I used to examine many diabetic patients.Besides treating them with drugs, I provided them with alkaline ionic water. After consuming alkalineionic water for one month, 15 diabetic patients were selected and sent to Tokyo University for furthertest and observations.Initially, the more serious patients were a bit apprehensive about the treatment. When the alkaline ionicwater was consumed for some time, the sugar in the blood and urine ranged from a ration of 300 mg/lto 2 mg/dc. There was a time where the patient had undergone 5 to 6 blood tests a day and detected tobe within normal range. Results also showed that even l l/2 hour after meals, the blood sugar and urineration was 100 mg/dc : 0 mg/dc. The sugar in the urine has completely disappeared.

    PRE-ECLAMPTIC TOXAEMIA

    Prof. Watanabe Ifao, Watanabe Hospital

    Alkaline ionic water improves body constituents and ensures effective healing to many illnesses. The uses of alkaline ionic water in gynaecological patients have proved to be very effective. The mainreason for its effectiveness is that this water can neutralise toxins.When given alkaline ionic water to pre-eclamptic toxaemia cases, the results are very significant.During my long years of servicing the pre-eclamptic toxaemia cases, I found that the women with pre-eclamptic toxaemia who consumed alkaline ionic water tend to deliver healthier babies with stronger

  3. BENEFITS of ALKALINE WATER CONSUMPTION
    For viewers not familiar with pH scales, pure acid is pH 0. Neutral (neither acid nor alkaline) is pH 7.
    Pure alkaline is pH 14.
    pH 7 is ten times more alkaline than pH 6.
    pH 8 is 100 times more alkaline than pH 6
    pH 9 is 1,000 times ore alkaline than pH 6

    For a little perspective, a well known cola is pH 2.5, meaning it is over 10,000 times more acid than neutral tap water, and 100,000 times more acid than your blood (pH 7.4)

    The Emco Tech Ionizers in the Ionlife range produce alkaline water frrom a pH 7.5 up to pH 11, depending on the setting you choose. The acidic water is not for drinking.

    Low alkaline settings: First time drinkers, children, pets.
    Medium alkaline settings: Experienced drinkers, tea, coffee, beverages, hangovers and jet lag rehydration.
    High alkaline Settings: Experienced drinkers, soups, casseroles, pasta.

    If detox symptoms are experienced as being too intense then reduce the level of alkaline pH.

  4. Electrolyzed Ionized Water Research
    By Heartspring Staff

    There are two types of water produced by a ionizer.

    Alkaline (Reduced) Water
    Acidic (Oxidizing) Water
    Academic Terms

    Water that is charged by the electrolytic cell of an ionizer, has various names:

    Electrolyzed Reduced Water (ERW) – Alkaline, or Acid
    Electrolytic Reduction Ion Water (ERI) – Alkaline, or Acid
    Electrolyzed Cathode Water (ECW) – Alkaline, Alkalized, Alkalization
    Electrolyzed Oxidizing Water (EOW)- Acidic water, Industrial applications
    Electrolyzed Anode Water (EAW) – Acidic
    Structured Water, Functional Water
    Dipole, Multipole WaterExit Site, KosmotrophesExit Site, Electrochemical, Electrolytic Redox, Layered Icosahedral Water, Tessellated, Declustered, Alkaline Water

    Marketing Terms

    Microwater, Ionized Water, Alkaline Antioxidant Water, Miracle Water, Kangen Water, Energy Water, Ion Water, Electrolyzer, Water Ionizer.

    Below is a collection of research abstracts describing the physiological effects of both alkaline (reduced) water and acidic (oxidizing)water. Use your browser’s back button to navigate the water ionizer research menu below.

    Alkaline Ionized Water Research

    Postgraduate Symposium: Positive influence of nutritional alkalinity on bone health
    Acid-base balance and hydration status following consumption of mineral-based alkaline bottled water.
    Hepatoprotective effect of electrolyzed reduced water against carbon tetrachloride-induced liver damage in mice.
    The immunological effects of electrolyzed reduced water on the Echinostoma hortense infection in C57BL/6 mice.
    Enhanced induction of mitochondrial damage and apoptosis in human leukemia HL-60 cells due to electrolyzed-reduced water and glutathione.
    Protective mechanism of reduced water against alloxan-induced pancreatic beta-cell damage.
    Electrolyzed Reduced Water Supplemented with Platinum Nanoparticles Suppresses Promotion of Two-stage Cell Transformation.
    Preservative effect of electrolyzed reduced water on pancreatic beta-cell mass in diabetic db/db mice.
    Anti-diabetic effects of electrolyzed reduced water in streptozotocin-induced and genetic diabetic mice.
    Electrolyzed-reduced water reduced hemodialysis-induced erythrocyte impairment in end-stage renal disease patients.
    Reduced hemodialysis-induced oxidative stress in end-stage renal disease patients by electrolyzed reduced water.
    Inhibitory effect of electrolyzed reduced water on tumor angiogenesis
    Electrolyzed-reduced water scavenges active oxygen & protects DNA from oxidative damage.
    Electrolyzed-reduced water protects against oxidative damage to DNA, RNA, and protein.
    The mechanism of the enhanced antioxidant effects of reduced water produced by electrolysis.
    Use of ionized water in hypochlorhydria, achlorhydria, reduction of high blood pressure
    Electrolyzed-reduced water inhibits acute ethanol-induced hangovers in Sprague-Dawley rats.
    Use of ionized water for gynecological conditions
    Clinical improvements obtained from the uptake of Ionized Water
    Alkaline ionized water for abdominal complaints: Placebo controlled double blind tests
    Stimulationof anaerobic microflora in the human intestinal tract by electrolyzed reducing water
    Physiological effects of alkaline ionized water: intestinal fermentation
    Effects of calcium alkaline ionized water on formation and maintenance of osseous tissues
    Use of Ionized water in heart disease and toxins.
    Use of Ionized water in eczema.
    Use of Ionized water in allergies.
    Use of Ionized water in diabetes treatment.
    Acidic Ionized Water – Electrolyzed Oxidizing Water Research

    Anti microbial interventions to reduce Salmonella species on poultry.
    Treatment of Escherichia coli inoculated alfalfa sprouts with electrolyzed oxidizing water.
    Inactivation of E. coli & Listeria on plastic kitchen cutting boards by electrolyzed oxidizing water.
    The bactericidal effects of electrolyzed oxidizing water on bacterial strains in hospital infections.
    Effect of electrolyzed water on wound healing.
    Effect of electrolyzed oxidizing water on excised burn-wounds in rats.
    Decomposition of ethylene, a flower-senescence hormone, with electrolyzed anode water.
    Alkaline Electrolyzed Reduced Water – Ionized Water

    Proc Nutrition Soc. 2010 Feb;69(1):166-73. Epub 2009 Dec 3.

    Postgraduate Symposium: Positive influence of nutritional alkalinity on bone health.

    Wynn E, Krieg MA, Lanham-New SA, Burckhardt P. University Hospital (CHUV), 1011 Lausanne, Switzerland.

    There is growing evidence that consumption of a Western diet is a risk factor for osteoporosis through excess acid supply, while fruits and vegetables balance the excess acidity, mostly by providing K-rich bicarbonate-rich foods. Western diets consumed by adults generate approximately 50-100 mEq acid/d; therefore, healthy adults consuming such a diet are at risk of chronic low-grade metabolic acidosis, which worsens with age as a result of declining kidney function. Bone buffers the excess acid by delivering cations and it is considered that with time an overstimulation of this process will lead to the dissolution of the bone mineral content and hence to reduced bone mass. Intakes of K, Mg and fruit and vegetables have been associated with a higher alkaline status and a subsequent beneficial effect on bone health. In healthy male volunteers an acid-forming diet increases urinary Ca excretion by 74% and urinary C-terminal telopeptide of type I collagen (C-telopeptide) excretion by 19% when compared with an alkali (base-forming) diet. Cross-sectional studies have shown that there is a correlation between the nutritional acid load and bone health measured by bone ultrasound or dual-energy X-ray absorptiometry. Few studies have been undertaken in very elderly women (>75 years), whose osteoporosis risk is very pertinent. The EVAluation of Nutrients Intakes and Bone Ultra Sound Study has developed and validated (n 51) an FFQ for use in a very elderly Swiss population (mean age 80.4 (sd 2.99) years), which has shown intakes of key nutrients (energy, fat, carbohydrate, Ca, Mg, vitamin C, D and E) to be low in 401 subjects. A subsequent study to assess net endogenous acid production (NEAP) and bone ultrasound results in 256 women aged > or = 75 years has shown that lower NEAP (P=0.023) and higher K intake (P=0.033) are correlated with higher bone ultrasound results. High acid load may be an important additional risk factor that may be particularly relevant in very elderly patients with an already-high fracture risk. The latter study adds to knowledge by confirming a positive link between dietary alkalinity and bone health indices in the very elderly. In a further study to complement these findings it has also been shown in a group of thirty young women that in Ca sufficiency an acid Ca-rich water has no effect on bone resorption, while an alkaline bicarbonate-rich water leads to a decrease in both serum parathyroid hormone and serum C-telopeptide. Further investigations need to be undertaken to study whether these positive effects on bone loss are maintained over long-term treatment. Mineral-water consumption could be an easy and inexpensive way of helping to prevent osteoporosis and could be of major interest for long-term prevention of bone loss. PMID:19954569

    Acid-base balance and hydration status following consumption of mineral-based alkaline bottled water.

    Heil DP. Journal of the Internation Society of Sports Nutrition, 2010 September 13;7(1):29.

    ABSTRACT: BACKGROUND: The present study sought to determine whether The consumption of a mineral-rich alkalizingbottled water could improve both acid-base balance and hydration status in young healthy adults under free-living conditions. The mineral-rich alkalizing bottled water contains a naturally high mineral content along with Alka-PlexLiquidTM, a dissolved supplement that increases the mineral content and gives the water an alkalizing pH of 10.0. METHODS: Thirty-eight subjects were matched by gender and self-reported physical activity (SRPA, hrs/week) and then split into Control (12 women, 7 men; Mean+/-SD: 23+/-2 yrs; 7.2+/-3.6 hrs/week SRPA) and Experimental (13 women, 6 men; 22+/-2 yrs; 6.4+/-4.0 hrs/week SRPA) groups. The Control group consumed non-mineralized placebo bottled water over a 4-week period while the Experimental group consumed the placebo water during the 1st and 4th weeks and the mineral-rich alkalizing bottled water during the middle 2-week treatment period. Fingertip blood and 24-hour urine samples were collected three times each week for subsequent measures of blood and urine osmolality and pH, as well as total urine volume. Dependent variables were analyzed using multivariate repeated measures ANOVA with post-hoc focused on evaluating changes over time within Control and Experimental groups (alpha = 0.05). RESULTS: There were no significant changes in any of the dependent variables for the Control group. The Experimental group, however, showed significant increases in both the blood and urine pH (6.23 to 7.07 and 7.52 to 7.69, respectively), a decreased blood and increased urine osmolality, and a decreased urine output (2.51 to 2.05 L/day), all during the second week of the treatment period (P<0.05). Further, these changes reversed for the Experimental group once subjects switched to the placebo water during the 4th week. CONCLUSIONS: Consumption of mineral-rich alkalizing bottled water was associated with improved acid-base balance (i.e., an alkalization of the blood and urine) and hydration status when consumed under free-living conditions. In contrast, subjects who consumed the placebo bottled water showed no changes over the same period of time. These results indicate that the habitual consumption of mineral-rich alkalizing bottled water may be a valuable nutritional vector for influencing both acid-base balance and hydration status in healthy adults. PMID:20836884

    Biomed Research. 2009 Oct;30(5):263-9.

    Electrolyzed-reduced water inhibits acute ethanol-induced hangovers in Sprague-Dawley rats.

    Park SK, Qi XF, Song SB, Kim DH, Teng YC, Yoon YS, Kim KY, Li JH, Jin D, Lee KJ. Department of Environmental Medical Biology, Wonju College of Medicine, Yonsei University, Wonju, Gangwon, Republic of Korea.

    Ethanol consumption disturbs the balance between the pro- and anti-oxidant systems of the organism, leading to oxidative stress. Electrolyzed-reduced water (ERW) is widely used by people in East Asia for drinking purposes because of its therapeutic properties including scavenging effect of reactive oxygen species. This study was performed to investigate the effect of ERW on acute ethanol-induced hangovers in Sprague-Dawley rats. Alcohol concentration in serum of ERW-treated rats showed significant difference at 1 h, 3 h and 5 h respectively as compared with the rats treated with distilled water. Both alcohol dehydrogenase type 1 and acetaldehyde dehydrogenase related with oxidation of alcohol were significantly increased in liver tissue while the level of aspartate aminotransferase and alanine aminotransferase in serum was markedly decreased 24 h after pre-oral administration of ERW. Moreover, oral administration of ERW significantly activated non-ezymatic (glutathione) and enzymatic (glutathione peroxidase, glutathione-S-transferase, Cu/Zn-superoxide dismutase and catalase) antioxidants in liver tissues compared with the control group. These results suggest that drinking ERW has an effect of alcohol detoxification by antioxidant mechanism and has potentiality for relief of ethanol-induced hangover symptoms. PMID:19887722

    Food Chemistry Toxicology. 2009 Aug;47(8):2031-6. Epub 2009 May 27.

    Hepatoprotective effect of electrolyzed reduced water against carbon tetrachloride-induced liver damage in mice.

    Tsai CF, Hsu YW, Chen WK, Chang WH, Yen CC, Ho YC, Lu FJ. Institute of Medicine, College of Medicine, Chung Shan Medical University, No. 110, Sec. 1, Jianguo N. Rd., Taichung 402, Taiwan.

    The study investigated the protective effect of electrolyzed reduced water (ERW) against carbon tetrachloride (CCl(4))-induced liver damage. Male ICR mice were randomly divided into control, CCl(4), CCl(4)+silymarin, and CCl(4)+ERW groups. CCl(4)-induced liver lesions include leukocytes infiltration, hepatocyte necrosis, ballooning degeneration, mitosis, calcification, fibrosis and an increase of serum alanine aminotransferase (ALT), and aminotransferase (AST) activity. In addition, CCl(4) also significantly decreased the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px). By contrast, ERW or silymarin supplement significantly ameliorated the CCl(4)-induced liver lesions, lowered the serum levels of hepatic enzyme markers (ALT and AST) and increased the activities of SOD, catalase, and GSH-Px in liver. Therefore, the results of this study show that ERW can be proposed to protect the liver against CCl(4)-induced oxidative damage in mice, and the hepatoprotective effect might be correlated with its antioxidant and free-radical scavenging effect. PMID:19477216

    Biological & Pharmaceutical Bulletin. 2009 Mar;32(3):456-62.

    The immunological effects of electrolyzed reduced water on the Echinostoma hortense infection in C57BL/6 mice.

    Lee KJ, Jin D, Chang BS, Teng YC, Kim DH. Department of Environmental Medical Biology, Wonju College of Medicine, Yonsei University, Gang Won, South Korea.

    Electrolyzed reduced water (ERW) is widely used for drinking by people in Asia. The purpose of this study was to examine the immunological effect of ERW on the immunity of animals by supplying ERW to C57BL/6 mice infected with Echinostoma hortense metacercariae. In the non-infected groups, interleukin (IL)-4 (p < 0.001), IL-5, IL-10, IL-1beta, tumor necrosis factor (TNF)-alpha and immunoglobulin (Ig) A expression of the group fed ERW (ERW group) increased in small intestine compared with the normal control group. In the case of infected groups, the group fed ERW (ERW+E. hortense group) showed the result that IL-4, IL-5, IL-10 and Ig A expression increased, but IL-1beta and TNF-alpha (p < 0.001) decreased, and the number of goblet cells (p < 0.001) and helix pomatia agglutinin (HPA) positive cells increased compared with the group without feeding ERW. However, adult worm recovery rate was markedly increased (p < 0.05). On the other hand, the expression of all the cytokines except IL-10 in spleen was mildly increased but not significant statistically, and there was no significant difference in the numerical changes of white blood cell (WBC). These results indicate that feeding ERW may have influence on the local immune response (Th-1 type cytokines such as IL-1beta, TNF-alpha) in the small intestine but not on the systemic immune response. PMID:19252295 Biological & Pharmaceutical Bulletin. 2009 Feb;73(2):280-7. Epub 2009 Feb 7. Enhanced induction of mitochondrial damage and apoptosis in human leukemia HL-60 cells due to electrolyzed-reduced water and glutathione. Tsai CF, Hsu YW, Chen WK, Ho YC, Lu FJ. Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan. Electrolzyed-reduced water (ERW) is a higher pH and lower oxidation-reduction potential water. In the present study, we examined the enhanced effect of ERW in the apoptosis of leukemia cells (HL-60) induced by glutathione (GSH). An enhanced inhibitory effect on the viability of the HL-60 cells was observed after treatment with a combination of ERW with various concentrations of GSH, whereas no cytotoxic effect in normal peripheral blood mononuclear cells was observed. The results of apoptotic related protein indicated that the induction of HL-60 cell death was caused by the induction of apoptosis through upregulation of Bax and downregulation of Bcl-2. The results of further investigation showed a diminution of intracellular GSH levels in ERW, and combination with GSH groups. These results suggest that ERW is an antioxidant, and that ERW, in combination with GSH, has an enhanced apoptosis-inducing effect on HL-60 cells, which might be mediated through the mitochondria-dependent pathway. PMID:19202298 Cytotechnology. 2002 Nov;40(1-3):139-49. Protective mechanism of reduced water against alloxan-induced pancreatic beta-cell damage: Scavenging effect against reactive oxygen species. Li Y, Nishimura T, Teruya K, Maki T, Komatsu T, Hamasaki T, Kashiwagi T, Kabayama S, Shim SY, Katakura Y, Osada K, Kawahara T, Otsubo K, Morisawa S, Ishii Y, Gadek Z, Shirahata S. Department of Genetic Resources Technology, Faculty of Agriculture, Kyushu University, 6-10-1 Hakozaki, Higashi-ku, Fukuoka, Japan. Reactive oxygen species (ROS) cause irreversible damage to biological macromolecules, resulting in many diseases. Reduced water (RW) such as hydrogen-rich electrolyzed reduced water and natural reduced waters like Hita Tenryosui water in Japan and Nordenau water in Germany that are known to improve various diseases, could protect a hamster pancreatic beta cell line, HIT-T15 from alloxan-induced cell damage. Alloxan, a diabetogenic compound, is used to induce type 1 diabetes mellitus in animals. Its diabetogenic effect is exerted via the production of ROS. Alloxan-treated HIT-T15 cells exhibited lowered viability, increased intracellular ROS levels, elevated cytosolic free Ca(2+) concentration, DNA fragmentation, decreased intracellular ATP levels and lowering of glucose-stimulated release of insulin. RW completely prevented the generation of alloxan-induced ROS, increase of cytosolic Ca(2+) concentration, decrease of intracellular ATP level, and lowering of glucose-stimulated insulin release, and strongly blocked DNA fragmentation, partially suppressing the lowering of viability of alloxan-treated cells. Intracellular ATP levels and glucose-stimulated insulin secretion were increased by RW to 2-3.5 times and 2-4 times, respectively, suggesting that RW enhances the glucose-sensitivity and glucose response of beta-cells. The protective activity of RW was stable at 4 degrees C for over a month, but was lost by autoclaving. These results suggest that RW protects pancreatic beta-cells from alloxan-induced cell damage by preventing alloxan-derived ROS generation. RW may be useful in preventing alloxan-induced type 1-diabetes mellitus. PMID:19003114 Cytotechnology. 2005 Jan;47(1-3):97-105. Electrolyzed Reduced Water Supplemented with Platinum Nanoparticles Suppresses Promotion of Two-stage Cell Transformation. Nishikawa R, Teruya K, Katakura Y, Osada K, Hamasaki T, Kashiwagi T, Komatsu T, Li Y, Ye J, Ichikawa A, Otsubo K, Morisawa S, Xu Q, Shirahata S. Department of Genetic Resources Technology, Faculty of Agriculture, Kyushu University, 6-10-1 Hakozaki, 812-8581, Higashi-ku, Fukuoka, Japan. In the two-stage cell transformation theory, cancer cells first receive initiation, which is mainly caused by DNA damage, and then promotion, which enhances transformation. Murine Balb/c 3T3 cells are widely used for transformation experiments because they lose contact inhibition ability when transformed. Electrolyzed reduced water (ERW), which is produced near a cathode during electrolysis of water, is an alkaline drinking water that is beneficial to health. ERW contains a high concentration of dissolved hydrogen and scavenge reactive oxygen species (ROS), along with a small amount of platinum (Pt) nanoparticles (Pt nps) derived from Pt-coated titanium electrodes. Pt nps stably disperse in aqueous solution for a long time, and convert hydrogen molecules to active hydrogen (atomic hydrogen) that can scavenge ROS. Therefore, ERW supplemented with synthesized Pt nps is a model strong reduced water. This is the first report that ERW supplemented with synthesized Pt nps strongly prevents transformation of Balb/c 3T3 cells. ERW was prepared by electrolysis of 0.002 M NaOH solution using a batch-type electrolysis device. Balb/c 3T3 cells were treated with 3-methyl cholanthrene (MCA) as an initiation substance, followed by treatment with phorbol-12-myristate-13-acetate (PMA) as a promotion substance. MCA/PMA-induced formation of a transformation focus was strongly suppressed by ERW supplemented with Pt nps but not by ERW or Pt nps individually. ERW supplemented with Pt nps suppressed transformation at the promoter stage, not at initiation, suggesting that ERW supplemented with Pt nps suppressed the PMA-induced augmentation of intracellular ROS. ERW supplemented with Pt nps is a potential new antioxidant against carcinogenesis. PMID:19003049 Biological & Pharmaceutical BulletinExit Site 2007 Feb;30(2):234-6 Preservative effect of electrolyzed reduced water on pancreatic beta-cell mass in diabetic db/db mice. Mi-Ja Kim1,2, Kyung Hee Jung,3 Yoon Kyung Uhm,3 Kang-Hyun Leem,4 and Hye Kyung Kim,5 1) Department of Obesity Management, Graduate School of Obesity Science, Dongduk Women's University 2) Imagine Obesity Institute, 117 Purynsol Mun Wa Gyun, Kyung Hee University 3) Department of Pharmacology, College of Medicine, Kyung Hee University 4) College of Korean Medicine, Semyung University 5) Department of Food and Biotechnology, Hanseo University Oxidative stress is produced under diabetic conditions and involved in progression of pancreatic beta-cell dysfunction. Both an increase in reactive oxygen free-radical species (ROS) and a decrease in the antioxidant defense mechanism lead to the increase in oxidative stress in diabetes. Electrolyzed reduced water (ERW) with ROS scavenging ability may have a potential effect on diabetic animals, a model for high oxidative stress. Therefore, the present study examined the possible anti-diabetic effect of ERW in genetically diabetic mouse strain C57BL/6J-db/db (db/db). ERW with ROS scavenging ability reduced the blood glucose concentration, increased blood insulin level, improved glucose tolerance and preserved beta-cell mass in db/db mice. The present data suggest that ERW may protects beta-cell damage and would be useful for antidiabetic agent. PMID:17268057 Life Science. 2006 Nov 10;79(24):2288-92. Epub 2006 Aug 2. Anti-diabetic effects of electrolyzed reduced water in streptozotocin-induced and genetic diabetic mice. Kim MJ, Kim HK. Department of Obesity management, Graduate School of Obesity Science, Dongduk Women's University, 23-1 Wolkgukdong, Seoul, 136-714, South Korea. Oxidative stress is produced under diabetic conditions and is likely involved in progression of pancreatic beta-cell dysfunction found in diabetes. Both an increase in reactive oxygen free-radical species (ROS) and a decrease in the antioxidant defense mechanism lead to the increase in oxidative stress in diabetes. Electrolyzed reduced water (ERW) with ROS scavenging ability may have a potential effect on diabetic animals, a model for high oxidative stress. Therefore, the present study examined the possible anti-diabetic effect of ERW in two different diabetic animal models. The genetically diabetic mouse strain C57BL/6J-db/db (db/db) and streptozotocin (STZ)-induced diabetic mouse were used as insulin deficient type 1 and insulin resistant type 2 animal model, respectively. ERW, provided as a drinking water, significantly reduced the blood glucose concentration and improved glucose tolerance in both animal models. However, ERW fail to affect blood insulin levels in STZ-diabetic mice whereas blood insulin level was markedly increased in genetically diabetic db/db mice. This improved blood glucose control could result from enhanced insulin sensitivity, as well as increased insulin release. The present data suggest that ERW may function as an orally effective anti-diabetic agent and merit further studies on its precise mechanism. PMID:16945392 Kidney Int. 2006 Jul;70(2):391-8. Epub 2006 Jun 7. Electrolyzed-reduced water reduced hemodialysis-induced erythrocyte impairment in end-stage renal disease patients. Huang KC, Yang CC, Hsu SP, Lee KT, Liu HW, Morisawa S, Otsubo K, Chien CT. Department of Family Medicine, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan. Chronic hemodialysis (HD) patients increase erythrocyte susceptibility to hemolysis and impair cell survival. We explored whether electrolyte-reduced water (ERW) could palliate HD-evoked erythrocyte impairment and anemia. Forty-three patients undergoing chronic HD were enrolled and received ERW administration for 6 month. We evaluated oxidative stress in blood and plasma, erythrocyte methemoglobin (metHb)/ferricyanide reductase activity, plasma metHb, and pro inflammatory cytokines in the chronic HD patients without treatment (n=15) or with vitamin C (VC)- (n=15), vitamin E (VE)-coated dialyzer (n=15), or ERW treatment (n=15) during an HD course. The patients showed marked increases (15-fold) in blood reactive oxygen species, mostly H(2)O(2), after HD without any treatment. HD resulted in decreased plasma VC, total antioxidant status, and erythrocyte metHb/ferricyanide reductase activity and increased erythrocyte levels of phosphatidylcholine hydroperoxide (PCOOH) and plasma metHb. Antioxidants treatment significantly palliated single HD course-induced oxidative stress, plasma and RBC PCOOH, and plasma metHb levels, and preserved erythrocyte metHb /ferricyanide reductase activity in an order VC>ERW>VE-coated dialyzer. However, ERW had no side effects of oxalate accumulation easily induced by VC. Six-month ERW treatment increased hematocrit and attenuated pro inflammatory cytokines profile in the HD patients. In conclusion, ERW treatment administration is effective in palliating HD-evoked oxidative stress, as indicated by lipid peroxidation, hemolysis, and overexpression of pro inflammatory cytokines in HD patients. PMID:16760903

    Reduced hemodialysis-induced oxidative stress in end-stage renal disease patients by electrolyzed reduced water.

    Kidney Int. 2003 Aug;64(2):704-14.

    Huang KC, Yang CC, Lee KT, Chien CT. Department of Family Medicine, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan.

    BACKGROUND: Increased oxidative stress in end-stage renal disease (ESRD) patients may oxidize macromolecules and consequently lead to cardiovascular events during chronic hemodialysis. Electrolyzed reduced water (ERW) with reactive oxygen species (ROS) scavenging ability may have a potential effect on reduction of hemodialysis-induced oxidative stress in ESRD patients. METHODS: We developed a chemiluminescence emission spectrum and high-performance liquid chromatography analysis to assess the effect of ERW replacement on plasma ROS (H2O2 and HOCl) scavenging activity and oxidized lipid or protein production in ESRD patients undergoing hemodialysis. Oxidized markers, dityrosine, methylguanidine, and phosphatidylcholine hydroperoxide, and inflammatory markers, interleukin 6 (IL-6), and C-reactive protein (CRP) were determined. RESULTS: Although hemodialysis efficiently removes dityrosine and creatinine, hemodialysis increased oxidative stress, including phosphatidylcholine hydroperoxide, and methylguanidine. Hemodialysis reduced the plasma ROS scavenging activity, as shown by the augmented reference H2O2 and HOCl counts (Rh2o2 and Rhocl, respectively) and decreased anti oxidative activity (expressed as total antioxidant status in this study). ERW administration diminished hemodialysis-enhanced Rh2o2 and Rhocl, minimized oxidized and inflammatory markers (CRP and IL-6), and partly restored total antioxidant status during 1-month treatment. CONCLUSION: This study demonstrates that hemodialysis with ERW administration may efficiently increase the H2O2- and HOCl-dependent antioxidant defense and reduce H2O2- and HOCl-induced oxidative stress. PMID:12846769

    Inhibitory effect of electrolyzed reduced water on tumor angiogenesis

    Biological & Pharmaceutical Bulletin. 2008 Jan;31(1):19-26

    Ye J, Li Y, Hamasaki T, Nakamichi N, Komatsu T, Kashiwagi T, Teruya K, Nishikawa R, Kawahara T, Osada K, Toh K, Abe M, Tian H, Kabayama S, Otsubo K, Morisawa S, Katakura Y,Shirahata S. Graduate School of Systems Life Sciences, Kyushu University, Higashi-ku, Fukuoka 812-8581, Japan

    Vascular endothelial growth factor (VEGF) is a key mediator of tumor angiogenesis. Tumor cells are exposed to higher oxidative stress compared to normal cells. Numerous reports have demonstrated that the intracellular redox (oxidation/reduction, ORP) state is closely associated with the pattern of VEGF expression. Electrolyzed reduced water (ERW) produced near the cathode during the electrolysis of water scavenged intracellular H(2)O(2) and decreased the release of H(2)O(2) from a human lung adenocarcinoma cell line, A549, and down-regulated both VEGF transcription and protein secretion in a time-dependent manner. To investigate the signal transduction pathway involved in regulating VEGF expression, mitogen-activated kinase (MAPK) specific inhibitors, SB203580 (p38 MAPK inhibitor), PD98059 (ERK1/2 inhibitor) and JNKi (c-Jun N-terminal protein kinase inhibitor) were applied. The results showed that only PD98059 blocks VEGF expression, suggesting an important role for ERK1/2 in regulating VEGF expression in A549 cells. As well, ERW inhibited the activation of extracellular signal-regulated kinase (ERK) in a time-dependent manner. Co-culture experiments to analyze in vitro tubule formation assay revealed that A549 cell-derived conditioned medium significantly stimulated the formation of vascular tubules in all analyzed parameters; tubule total area, tubule junction, number of tubules, and total tubule length. ERW counteracted the effect of A549 cell-conditioned medium and decreased total tube length (p<0.01). The present study demonstrated that ERW down-regulated VEGF gene transcription and protein secretion through inactivation of ERK. Full Text

    Related Research:
    Levels of Soluble Vascular Endothelial Growth Factor (VEGF) Receptor 1 in Astrocytic Tumors and Its Relation to Malignancy, Vascularity, and VEGF-A

    Preservative Effect of Electrolyzed Reduced Water on Pancreatic Beta-Cell Mass in Diabetic db/db Mice

    Biological & Pharmaceutical Bulletin 2007 Feb;30(2):234-6

    Mi-Ja Kim1,2, Kyung Hee Jung,3 Yoon Kyung Uhm,3 Kang-Hyun Leem,4 and Hye Kyung Kim,5

    1) Department of Obesity Management, Graduate School of Obesity Science, Dongduk Women's University
    2) Imagine Obesity Institute, 117 Purynsol Mun Wa Gyun, Kyung Hee University
    3) Department of Pharmacology, College of Medicine, Kyung Hee University
    4) College of Korean Medicine, Semyung University
    5) Department of Food and Biotechnology, Hanseo University

    Oxidative stress is produced under diabetic conditions and involved in progression of pancreatic β-cell dysfunction. Both an increase in reactive oxygen free-radical species (ROS) and a decrease in the antioxidant defense mechanism lead to the increase in oxidative stress in diabetes. Electrolyzed reduced water (ERW) with ROS scavenging ability may have a potential effect on diabetic animals, a model for high oxidative stress. Therefore, the present study examined the possible anti-diabetic effect of ERW in genetically diabetic mouse strain C57BL/6J-db/db (db/db). ERW with ROS scavenging ability reduced the blood glucose concentration, increased blood insulin level, improved glucose tolerance and preserved β-cell mass in db/db mice. The present data suggest that ERW may protects β-cell damage and would be useful for antidiabetic agent.

    Related Research:Involvement of Oxidative Stress and the JNK Pathway in Glucose Toxicity

    Anticancer Effect of Alkaline Reduced Water

    By the Department of Parasitology, Institute of Basic Medical Sciences, Department of Microbiology, Department of Biochemistry, Wonju College of MedicineExit Site, Yonsei University Department of Biomedical Laboratory Science and Institute of Health Science, College of Health Science, Yonsei UniversityExit Site.

    Certain minerals can produce alkaline reduced water with high pH and low oxidation-reduction potential (ORP) when dissolved in water. Alkaline reduced water showed significant anticancer effect. When B16 melanoma cells were inoculated subcutaneous and intra-peritoneally, C56BL/6 mice fed with alkaline reduced water showed tumor growth delay and the survival span was significantly lengthened. Alkaline reduced water also showed the inhibition of metastasisExit Site by reducing the numbers of B16 melanoma colonies when injected through tail vein. The amount of reactive oxygen speciesExit Site (ROS) was very reduced when fed with alkaline reduced water except for spleen, which is a major organ for immunity. Even for normal mice, alkaline reduced water intake invoked systemic cytokines, such as, Th1 (IFN-g, IL-12) and Th2 (IL-4, IL-5), suggesting strong immuno-modulation effect. Both ROS scavenging effect and immuno-modulation effect might be responsible for anticancer effect of alkaline reduced water. Continue reading the full study

    Electrolyzed-reduced water scavenges active oxygen species and protects DNA from oxidative damage.

    Biochemistry Biophysical Research Communications. 1997 May 8;234(1):269-74.

    Shirahata S, Kabayama S, Nakano M, Miura T, Kusumoto K, Gotoh M, Hayashi H, Otsubo K, Morisawa S, Katakura Y.

    Institute of Cellular Regulation Technology, Graduate School of Genetic Resources Technology, Kyushu University, Fukuoka, Japan.

    Active oxygen species or free-radicals are considered to cause extensive oxidative damage to biological macromolecules, which brings about a variety of diseases as well as aging. The ideal scavenger for active oxygen should be 'active hydrogen'. 'Active hydrogen' can be produced in reduced water near the cathode during electrolysis of water. Reduced water exhibits high pH, low dissolved oxygen (DO), extremely high dissolved molecular hydrogen (DH), and extremely negative redox potential (RP) values. Strongly electrolyzed-reduced water, as well as ascorbic acid, (+)-catechin and tannic acid, completely scavenged O.-2 produced by the hypoxanthine-xanthine oxidase (HX-XOD) system in sodium phosphate buffer (pH 7.0). The superoxide dismutase (SOD)-like activity of reduced water is stable at 4 degrees C for over a month and was not lost even after neutralization, repeated freezing and melting, deflation with sonication, vigorous mixing, boiling, repeated filtration, or closed autoclaving, but was lost by opened autoclaving or by closed autoclaving in the presence of tungsten trioxide which efficiently adsorbs active atomic hydrogen. Water bubbled with hydrogen gas exhibited low DO, extremely high DH and extremely low RP values, as does reduced water, but it has no SOD-like activity. These results suggest that the SOD-like activity of reduced water is not due to the dissolved molecular hydrogen but due to the dissolved atomic hydrogen (active hydrogen). Although SOD accumulated H2O2 when added to the HX-XOD system, reduced water decreased the amount of H2O2 produced by XOD. Reduced water, as well as catalase and ascorbic acid, could directly scavenge H2O2. Reduced water suppresses single-strand breakage of DNA b active oxygen species produced by the Cu(II)-catalyzed oxidation of ascorbic acid in a dose-dependent manner, suggesting that reduced water can scavenge not only O2.- and H2O2, but also 1O2 and .OH. PMID:9169001

    Electrolyzed-reduced water protects against oxidative damage to DNA, RNA, and protein.

    Appl Biochemistry Biotechnol. 2006 Nov;135(2):133-44.

    Lee MY, Kim YK, Ryoo KK, Lee YB, Park EJ. Department of Genetic Engineering, Soonchunhyang University, Asan, Chungnam 336-600, Korea.

    The generation of reactive oxygen species is thought to cause extensive oxidative damage to various biomolecules such as DNA, RNA, and protein. In this study, the preventive, suppressive, and protective effects of in vitro supplementation with electrolyzed-reduced water on H2O2-induced DNA damage in human lymphocytes were examined using a comet assay. Pre-treatment, co-treatment, and post-treatment with electrolyzed-reduced water enhanced human lymphocyte resistance to the DNA strand breaks induced by H2O2 in vitro. Moreover, electrolyzed-reduced water was much more effective than diethylpyrocarbonate-treated water in preventing total RNA degradation at 4 and 25 degrees C. In addition, electrolyzed-reduced water completely prevented the oxidative cleavage of horseradish peroxidase, as determined using sodium dodecyl sulfate-polyacrylamide gels. Enhancement of the antioxidant activity of ascorbic acid dissolved in electrolyzed-reduced water was about threefold that of ascorbic acid dissolved in nonelectrolyzed deionized water, as measured by a xanthine-xanthine oxidase superoxide scavenging assay system, suggesting an inhibitory effect of electrolyzedreduced water on the oxidation of ascorbic acid. PMID:17159237

    Biophysical Chemistry. 2004 Jan 1;107(1):71-82.

    The mechanism of the enhanced antioxidant effects against superoxide anion radicals of reduced water produced by electrolysis.

    Hanaoka K, Sun D, Lawrence R, Kamitani Y, Fernandes G.

    Bio-REDOX Laboratory Inc. 1187-4, Oaza-Ueda, Ueda-shi, Nagano-ken 386-0001, Japan.

    We reported that reduced water produced by electrolysis enhanced the antioxidant effects of proton donors such as ascorbic acid (AsA) in a previous paper. We also demonstrated that reduced water produced by electrolysis of 2 mM NaCl solutions did not show antioxidant effects by itself. We reasoned that the enhancement of antioxidant effects may be due to the increase of the ionic product of water as solvent. The ionic product of water (pKw) was estimated by measurements of pH and by a neutralization titration method. As an indicator of oxidative damage, Reactive Oxygen Species- (ROS) mediated DNA strand breaks were measured by the conversion of supercoiled phiX-174 RF I double-strand DNA to open and linear forms. Reduced water had a tendency to suppress single-strand breakage of DNA induced by reactive oxygen species produced by H2O2/Cu (II) and HQ/Cu (II) systems. The enhancement of superoxide anion radical dismutation activity can be explained by changes in the ionic product of water in the reduced water. PMID:14871602 [PubMed]

    Use of Ionized water in hypochlorhydria or achlorhydria

    Prof. Kuninaka Hironage, Head of Kuninaka Hospital

    "Too many fats in the diets, which lead to the deposition of cholesterol on the blood vessels, which in turn constrict the blood flow, cause most illnesses such as high blood pressure. In accordance with the theory of Professor Gato of Kyushu University on Vitamin K (because vitamin K enables the blood calcium to increase ), or The consumption of more antioxidant water, the effectiveness of the increase in the calcium in high blood pressure is most significant. The consumption of alkaline antioxidant water for a period of 2 to 3 months, I have observed the blood pressure slowly drop, due to the water's solvent ability, which dissolves the cholesterol in the blood vessels.

    Use of Ionized water for gynecological conditions

    Prof. Watanabe Ifao, Watanabe Hospital

    "Ionized alklaine antioxidant water improves body constituents and ensures effective healing to many illnesses. The uses of antioxidant water in gynecological patients have proved to be very effective. The main reason for its effectiveness is that this water can neutralize toxins.

    When given antioxidant water to pre-eclamptic toxemia cases, the results are most significant. During my long years of servicing the pre-eclamptic toxemia cases, I found that the women with pre-eclamptic toxemia who consumed antioxidant water tend to deliver healthier babies with stronger muscles. A survey report carried out on babies in this group showed intelligence above average.

    Toxin Neutralization

    Prof. Kuwata Keijiroo, Doctor of Medicine

    "In my opinion, the wonder of antioxidant water is the ability neutralizes toxins, but it is not a medicine. The difference is that the medicine can only apply to each and individual case, whereas the antioxidant water can be consumed generally and its neutralizing power is something which is very much unexpected. Now, in brief, let me introduce to you a heart disease case and how it was cured.

    The patient was a 35 years old male suffering from vascular heart disease. For 5 years, his sickness deteriorated. He was in the Setagays Government Hospital for treatment.

    During those 5 years, he had been in and out of the hospital 5 to 6 times. He had undergone high tech examinations such as angiogram by injecting VINYL via the vein into the heart. He consulted and sought treatment from many good doctors where later he underwent a major surgical operation. Upon his discharge from the hospital, he quit his job to convalesce. However, each time when his illness relapsed, the attack seemed to be even more severe.

    Last year, in August, his relatives were in despair and expected he would not live much longer. It so happened at that time that the victim's relative came across antioxidant water processor. His illness responded well and he is now on the road to recovery."

    (In the United States, cardiovascular diseases account for more than one-half of the approximate 2 million deaths occurring each year…. It is estimated that optimal conditioning of drinking water could reduce this cardiovascular disease mortality rate by as much as 15 percent in the United States) - Report of the Safe Drinking Water Committee of the National Academy of Sciences, 1977

    Eczema

    Prof. Tamura Tatsuji, Keifuku Rehabilitation Center

    "Eczema is used to describe several varieties of skin conditions, which have a number of common features. The exact cause or causes of eczema are not fully understood. I many cases, eczema can be attributed by external irritants.

    Let me introduce a patient who recovered from skin disease after consuming the antioxidant water. This patient suffered 10 years of eczema and could not be reversed effectively even under specialist treatment. This patient, who is 70 years of age, is the president of a vehicle spare parts company. After the war, his lower limbs suffered acute eczema, which later became chronic. He was repeatedly treated in a specialist skin hospital.

    The left limb responded well to treatment, but not so on the right limb. He suffered severe itchiness, which, when scratched led to bleeding. During the last 10 years, he was seen and treated by many doctors. When I first examined him, his lower limb around the joints was covered with vesicles. Weeping occurred owing to serum exuding from the vesicles.

    I advised him to try consuming antioxidant water. He bought a unit and consumed the antioxidant water religiously and used the acidic water to bathe the affected areas. After 2 weeks of treatment the vesicles dried up. The eczema was completely cleared without any relapse after 1½ month."

    Allergies

    Prof. Kuninaka Hironaga, Head of Kuninaka Hospital

    "Mr. Yamada, the head of Police Research Institute, suffered from severe allergy. He was treated repeatedly by skin specialist, but with no success. Then he started consuming antioxidant water. The allergy responded very well and was soon completely cured. No relapse had occurred, although he had taken all kinds of food. He was most grateful and excited about this treatment.

    As for myself, I had also suffered severe allergy. Ever since I began to consume antioxidant water, the allergy has recovered. Since then, I started a research on the effectiveness of antioxidant water.

    I discovered that most allergies are due to acidification of body condition and is also related to consuming too much meat and sugar. In every allergy case, the patient's antioxidant minerals are excessively low which in turn lower the body resistance significantly. The body becomes overly sensitive and develops allergy easily. To stabilize the sensitivity, calcium solution in injected into the vein. Therefore, it is clear that the antioxidant water has ionic calcium, which can help alleviate allergy.

    The ionic calcium not only enhances the heart, urination, and neutralization of toxins but controls acidity. It also enhances the digestive system and liver function. This will promote natural healing power and hence increase its resistance to allergy. In some special cases of illness, which do not respond to drugs, it is found, it is found to respond well to antioxidant water."

    Digestive Problems

    Prof. Kogure Keizou, Kogure Clinic of Juntendo Hospital

    "The stomach is readily upset both by diseases affecting the stomach and by other general illnesses. In addition, any nervous tension or anxiety frequently causes gastric upset, vague symptoms when This information is under some strain.

    The important role of antioxidant water in our stomach is to neutralize the secretion and strengthen it s functions. Usually, after consuming the antioxidant water for 1 to 3 minutes, the gastric juice increase to 1½ times. For those suffering from hypochlorhydria or achlorhydria ( low in gastric juice ) the presence of antioxidant water will stimulate the stomach cells to secrete more gastric juice. This in turn enhances digestion and absorption of minerals.

    However, on the other hand, those with hyperchlorhydria ( high in gastric juice ), the antioxidant water neutralizes the excessive gastric juice. Hence, it does not create any adverse reaction.

    According to the medical lecturer from Maeba University, the pH of the gastric secretion will still remain normal when antioxidant water is consumed. This proves that the ability of the antioxidant water is able to neutralize as well as to stimulate the secretion."

    Diabetes

    Prof. Kuwata Keijiroo, Doctor of Medicine

    "When I was serving in the Fire Insurance Association, I used to examine many diabetic patients. Besides treating them with drugs, I provided them with antioxidant water. After drinking antioxidant water for one month, 15 diabetic patients were selected and sent to Tokyo University for further test and observations.

    Initially, the more serious patients were a bit apprehensive about the treatment. When the antioxidant water was consumed for some time, the sugar in the blood and urine ranged from a ratio of 300 mg/l to 2 mg / dc. There was a time where the patient had undergone 5 to 6 blood tests a day and detected to be within normal range. Results also showed that even 1 ½ hour after meals, the blood sugar and urine ratio was 100 mg/dc: 0 mg/dc . The sugar in the urine has completely disappeared."

    NOTE:
    More Americans than ever before are suffering from diabetes, with the number of new cases averaging almost 800,000 each year. The disease has steadily increased in the United States since 1980, and in 1998, 16 million Americans were diagnosed with diabetes (10.3 million diagnosed; 5.4 million undiagnosed). Diabetes is the seventh leading cause of death in the United States, and more than 193,000 died from the disease and its related complication in 1996. The greatest increase - 76 percent - occurred in people age 30 to 30.

    From: U. S. Department of Health and Human Services, October 13, 2000 Fact Sheet

    Clinical Impovements Obtained From The Intake Of Reduced Water

    Extracts from " Presentation At The Eight Annual International Symposium On man And His Environment in Health And Disease" on February 24th 1990, at The Grand Kempinski Hotel, Dalls, Texas, USA by Dr. H. Hayashi, M.D. and Dr. M Kawamura, M.D., on : -

    THE CONCEPT OF PREHEPATIC MEDICINES

    Since the introduction of alkaline ionic water in our clinic in 1985, we have had the following interesting clinical experiences in the use of this type of water. By the use of alkaline ionic water for drinking and the preparation of meals for our in-patients, we have noticed :

    Declines in blood sugar levels in diabetic patients.
    Improvements in peripheral circulation in diabetic gangrene.
    Declines in uric acid levels in patients with gout.
    Improvements in liver function exams in hepatic disorders.
    Improvements in gastroduodenal ulcer and prevention of their recurrences.
    Improvements in hypertension and hypotension.
    Improvements in allergic disorders such as asthma, urticaria, rhinites and atopic dermatitis.
    Improvements in persistent diarrhoea which occurred after gastrectomy.
    Quicker improvements in post operative bower paralysis.
    Improvements in serum bilirubin levels in new born babies.

    Being confirming clinical improvements, we have always observed changes of stools of the patients, with the colour of their feaces changing from black-brown colour to a brigher yellow-brown one, and the odour of their feaces becoming almost negligible.

    The number of patients complaining of constipation also decreased markedly. The change of stool findings strongly suggests that alkaline ionic water intake can decrease the production of putrefield or pathogenic metabolites.

    Devices to produce reduced water were introduced into our clinic in May 1985. Based on the clinical experiences obtained in the past 15 years, it can be said that introduction of electrolyzed-reduced water for drinking and cooking purpose for in-patients should be the very prerequisite in our daily medical practices. Any dietary recipe cannot be a scientific one if property of water is not taken by the patients is not taken into consideration.

    The Ministry of Health and Welfare in Japan announced in 1965 that the intake of reduced water is effective for restoration of intestinal flora metabolism.

    Selective stimulation of the growth of anaerobic microflora in the human intestinal tract by electrolyzed reducing water

    By the Department of Physiology of Microorganisms, Lomonosov Moscow State University

    96-99% of the "friendly" or residential microflora of intestinal tract of humans consists of strict anaerobes and only 1-4% of aerobes. Many diseases of the intestine are due to a disturbance in the balance of the microorganisms inhabiting the gut. The treatment of such diseases involves the restoration of the quantity and/or balance of residential microflora in the intestinal tract. It is known that aerobes and anaerobes grow at different oxidation-reduction potentials (ORP). The former require positive E(h) values up to +400 mV. Anaerobes do not grow unless the E(h) value is negative between -300 and -400 mV. In this work, it is suggested that prerequisite for the recovery and maintenance of obligatory anaerobic microflora in the intestinal tract is a negative ORP value of the intestinal milieu. Electrolyzed reducing water with E(h) values between 0 and -300 mV produced in electrolysis devices possesses this property. Drinking such water favours the growth of residential microflora in the gut. A sufficient array of data confirms this idea. However, most researchers explain the mechanism of its action by an antioxidant properties destined to detox the oxidants in the gut and other host tissues. Evidence is presented in favour of the hypothesis that the primary target for electrolyzed reducing water is the residential microflora in the gut.
    PMID:15617863 [PubMed]

    Vorobjeva NV. Department of Physiology of Microorganisms, Biology Faculty, Lomonosov Moscow State University, 119992 Moscow, Russia. Medical Hypotheses. 2005;64(3):543-6.

    Clinical evaluation of alkaline ionized water for abdominal complaints: Placebo controlled double blind tests

    by Hirokazu Tashiro, Tetsuji Hokudo, Hiromi Ono, Yoshihide Fujiyama, Tadao Baba (National Ohkura Hospital, Dept. of Gastroenterology; Institute of Clinical Research, Shiga University of Medical Science, Second Dept. of International Medicine)

    Effect of alkaline ionized water on abdominal complaints was evaluated by placebo controlled double blind tests. Overall scores of improvement using alkaline ionized water marked higher than those of placebo controlled group, and its effect proved to be significantly higher especially in slight symptoms of chronic diarrhoea and abdominal complaints in cases of general malaise. Alkaline ionized water group did not get interrupted in the course of the test, nor did it show serious side effects nor abnormal test data. It was confirmed that alkaline ionized water is safer and more effective than placebos.

    Summary

    Effect of alkaline ionized water on abdominal complaints was clinically examined by double blind tests using clean water as placebo. Overall improvement rate was higher for alkaline ionized water group than placebo group and the former proved to be significantly more effective than the other especially in cases of slight symptoms. Examining improvement rate for each case of chronic diarrhoea, constipation and abdominal complaints, alkaline ionized water group turned out to be more effective than placebo group for chronic diarrhoea, and abdominal complaints. The test was stopped in one case of chronic diarrhoea, among placebo group due to exacerbation, whereas alkaline ionized water group did not stop testing without serious side effects or abnormal test data in all cases. It was confirmed that alkaline ionized water is more effective than clean water against chronic diarrhoea, abdominal complaints and overall improvement rate (relief of abdominal complaints) and safer than clean water.

    Introduction

    Since the approval of alkaline ionized water electrolyzers by Pharmaceutical Affairs Law in 1966 for its antacid effect and efficacy against gastrointestinal disorders including hyperchylia, indigestion, abnormal gastrointestinal fermentation and chronic diarrhoea, they have been extensively used among patients. However, medical and scientific evaluation of their validity is not established. In our study, we examined clinical effect of alkaline ionized water on gastrointestinal disorders across many symptoms in various facilities. Particularly, we studied safety and usefulness of alkaline ionized water by doubleblind tests using clean water as a control group.

    Test subjects and methods

    163 patients (34 men, 129 women, age 21 to 72, average 38.6 years old) of indigestion, abnormal gastrointestinal fermentation (with abnormal gas emission and rugitus) and abdominal complaints caused by irregular dejection (chronic diarrhoea, or constipation) were tested as subjects with good informed consent. Placebo controlled double blind tests were conducted using alkaline ionized water and clean water at multiple facilities. An alkaline ionized water electrolyzer sold commercially was installed with a pump driven calcium dispenser in each of the subject homes. Tested alkaline ionized water had pH at 9.5 and calcium concentration at 30ppm. Each subject in placebo group used a water purifier that has the same appearance as the electrolyzer and produces clean water.

    The tested equipment was randomly assigned by a controller who scaled off the key code which was stored safely until the tests were completed and the seal was opened again.

    Water samples were given to each patient in the amount of 200ml in the morning with the total of 50OmI or more per day for a month. Before and after the tests, blood, urine and stool were tested and a log was kept on the subjective symptoms, bowel movements and accessory symptoms. After the tests, the results were analyzed based on the log and the test data.

    Water Ionizer Test Results

    1. Symptoms

    Among 163 tested subjects, alkaline ionized water group included 84 and placebo group 79. Background factors such as gender, age and basal disorders did not contribute to significant difference in the results.

    2. Overall improvement rate

    As to overall improvement rate of abdominal complaints, alkaline ionized water group had 2 cases of outstanding improvement (2.5%), 26 cases of fair improvement (32.1%), 36 cases of slight improvement (44.4%), 13 cases of no change (16%) and 4 cases of exacerbation (4.9%), whereas placebo group exhibited 4 (5.2%), 19 (24.7%), 27 (35.1%), 25 (32.5%) and 2 cases (2.6%) for the same category. Comparison between alkaline ionized water and placebo groups did not reveal any significant difference at the level of 5% significance according to the Wilcoxon test, although alkaline ionized water group turned out to be significantly more effective than placebo group at the level of p value of 0.22.

    Examining overall improvement rates by a 7, 2 test (with no adjustment for continuity) between the effective and noneffective groups, alkaline ionized water group had 64 (79%) of effective cases and 17 cases (21%) of non effective cases, whereas placebo group had 50 (64.9%) and 27 (35.1%) cases respectively. The result indicated that alkaline ionized water group was significantly more effective than placebo group at the level of p value of 0.0.48.

    Looking only at 83 slight cases of abdominal complaints, overall improvement rate for alkaline ionized water group

    (45 cases) was composed of 11 cases (242%) of fair improvement, 22 cases (48.9%) of slight improvement, 17 cases (44.7%) of no change and 3 cases (6.7%) of exacerbation, whereas placebo group (38 cases) had 3 (7.8%), 17 (44.7%), 17 (44.7%) and 1 (2.6%) cases for the same category. Alkaline ionized water group was significantly more effective than placebo group according to the comparison between the groups (p value = 0.033).

    3. Improvement rate by basal symptom

    Basal symptoms were divided into chronic diarrhea, constipation and abdominal complaints (dyspepsia) and overall improvement rate was evaluated for each of them to study effect of alkaline ionized water. In case of chronic diarrhoea, alkaline ionized water group resulted in 94.1% of effective cases and 5.9% of non effective cases. Placebo group came up with 64,7% effective and 35.3% non effective. These results indicate alkaline ionized water group proved to be significantly more effective than placebo group. In case of slighter chronic diarrhoea, comparison between groups revealed that alkaline ionized water group is significantly more effective than placebo group (p=0.015). In case of constipation, alkaline ionized water group consisted of 80.5% of effective and 19.5% of non effective cases, whereas placebo group resulted in 73.3% effective and 26.3 non effective. As to abdominal complaints (dyspepsia), alkaline ionized water group had 85.7% of effective and 14.3% non effective cases while placebo group showed 47.1% and 62.9% respectively. Alkaline ionized water group proved to be significantly more effective than placebo group (p=0.025).

    4. Safety

    Since one case of chronic diarrhoea, in placebo group saw exacerbation, the test was stopped. There was no such cases in alkaline ionized water group. Fourteen cases of accessory symptoms, 8 in alkaline ionized water group and 6 in placebo group, were observed, none of which were serious. 31 out of 163 cases (16 in alkaline ionized water group, 15 in placebo group) exhibited fluctuation in test data, although alkaline ionized water group did not have any problematic fluctuations compared to placebo group. Two cases in placebo group and one case in alkaline ionized water group have seen K value of serum climb up and resume to normal value after re testing which indicates the value changes were temporary.

    Conclusion

    As a result of double blind clinical tests of alkaline ionized water and clean water, alkaline ionized water was proved to be more effective than clean water against chronic diarrhoea, abdominal complaints (dyspepsia) and overall improvement rate (relief from abdominal complaints). Also, safety of alkaline ionized water was confirmed which clinically verifies its usefulness.

    Physiological effects of alkaline ionized water:

    Effects on metabolites produced by intestinal fermentation

    by Takashi Hayakawa, Chicko Tushiya, Hisanori Onoda, Hisayo Ohkouchi, Harul-~to Tsuge (Gifu University, Faculty of Engineering, Dept. of Food Science)

    We have found that long-term ingestion of alkaline ionized water (alkaline ionized water) reduces cecal fermentation in rats that were given highly fermentable commercial diet (MF: Oriental Yeast Co., Ltd.). In this experiment, rats were fed MF and test water (tap water, alkaline ionized water with pH at 9 and 10) for about 3 months. Feces were collected on the 57th day, and the rats were dissected on the 88th day. The amount of ammonium in fresh feces and cecal contents as well as fecal free-glucose tended to drop down for the alkaline ionized water group. In most cases, the amount of free-amino acids in cecal contents did not differ signicantly except for cysteine (decreased in alkaline ionized water with pH at 10) and isoleucine (increased in alkaline ionized water with pH at 10).

    Purpose of tests

    Alkaline ionized water electrolyzers have been approved for manufacturing in 1965 by the Ministry of Health and Welfare as medical equipment to produce medical substances. Alkaline ionized water (alkaline ionized water) produced by this equipment is known to be effective against gastrointestinal fermentation, chronic diarrhea, indigestion and hyperchylia as well as for controlling gastric acid.*1 This is mainly based on efficacy of the official calcium hydroxide. *2 By giving alkaline ionized water to rats for a comparatively long time under the condition of extremely high level of intestinal fermentation, we have demonstrated that alkaline ionized water intake is effective for inhibition of intestinal fermentation when its level is high based on some test results where alkaline ionized water worked against cecal hypertrophy and for reduction in the amount of short-chain fatty acid that is the main product of fermentation.*3 We have reported that this is caused by the synergy between calcium level generally contained in alkaline ionized water (about 50ppm) and the value of pH, and that frequency of detecting some anaerobic bacteria tends to be higher in alkaline ionized water groups than the other, although the bacteria count in the intestine does not have significant difference. Based on these results, we made a judgment that effect of taking alkaline ionized water supports part of inhibition mechanism against abnormal intestinal fermentation, which is one of the claims of efficacy that have been attributed to alkaline ionized water electrolyzers. *4 On the other hand, under the dietary condition of low intestinal fermentation, alkaline ionized water uptake does not seem to inhibit fermentation that leads us to believe that effect of alkaline ionized water uptake is characteristic of hyper-fermentation state. Metabolites produced by intestinal fermentation include indole and skatole in addition to organic acids such as short-chain fatty acid and lactic acid as well as toxic metabolites such as ammonium, phenol and pcresol. We do not know how alkaline ionized water uptake would affect the production of these materials. In this experiment, we have tested on ammonium production as explained in the following sections.

    Testing methods

    Four-week-old male Wistar/ST Clean rats were purchased from Japan SLC Co., Ltd. and were divided into 3 groups of 8 each after preliminary breeding. alkaline ionized water of pH 9 and 10 was produced by an electrolyzer Mineone ROYAL NDX3 1 OH by Omco Co., Ltd. This model produces alkaline ionized water by electrolyzing water with calcium lactate added. On the last day of testing, the rats were dissected under Nembutal anesthesia to take blood from the heart by a heparin-treated syringe. As to their organs, the small intestines, cecum and colon plus rectum were taken out from each of them. The cecurn was weighed and cleaned with physiological saline after its contents were removed, and the tissue weight was measured after wiping out moisture. Part of cecal contents was measured its pH, and the rest was used to assay ammonium concentration. The amount of ammonium contained in fresh feces and cecal contents was measured by the Nessler method after collecting it in the extracted samples using Conway's micro-diffusion container. Fecal free-glucose was assayed by the oxygen method after extraction by hot water. Analysis of free amino acids contained in cecal contents was conducted by the Waters PicoTag amino acid analysis system.

    Test results and analyses

    No difference was found in the rats' weight gain, water and feed intake and feeding efficiency, nor was any particular distinction in appearance identified. The length of the small intestines and colon plus rectum tended to decline in alkaline ionized water groups. PH value of cecal contents was higher and the amount of fecal free-glucose tended to be lower in alkaline ionized water groups than the control group. Since there was no difference in fecal discharge itself, the amount of free-glucose discharged per day was at a low level. The amount of discharged free-glucose in feces is greater when intestinal fermentation is more intensive, which indicates that intestinal fermentation is more inhibited in alkaline ionized water groups than the control group. Ammonium concentration in cecal contents tends to drop down in alkaline ionized water groups (Fig. 1). This trend was most distinctive in case of fresh feces of one of alkaline ionized water groups with

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