Tag Archives: acqua ionizzata alcalina

ionized alkaline water reduces HEMODIALYSIS-induced oxidative stress in END-STAGE RENAL DISEASE patients

 

Abstract

BACKGROUND:

Increased oxidative stress in end-stage renal disease (ESRD) patients may oxidize macromolecules and consequently lead to cardiovascular events during chronic hemodialysis. Electrolyzed reduced water (ERW) with reactive oxygen species (ROS) scavenging ability may have a potential effect on reduction of hemodialysis-induced oxidative stress in ESRD patients.

METHODS:

We developed a chemiluminescence emission spectrum and high-performance liquid chromatography analysis to assess the effect of ERW replacement on plasma ROS (H2O2 and HOCl) scavenging activity and oxidized lipid or protein production in ESRD patients undergoing hemodialysis. Oxidized markers, dityrosine, methylguanidine, and phosphatidylcholine hydroperoxide, and inflammatory markers, interleukin 6 (IL-6), and C-reactive protein (CRP) were determined.

RESULTS:

Although hemodialysis efficiently removes dityrosine and creatinine, hemodialysis increased oxidative stress, including phosphatidylcholine hydroperoxide, and methylguanidine. Hemodialysis reduced the plasma ROS scavenging activity, as shown by the augmented reference H2O2 and HOCl counts (Rh2o2 and Rhocl, respectively) and decreased antioxidative activity (expressed as total antioxidant status in this study). ERW administration diminished hemodialysis-enhanced Rh2o2 and Rhocl, minimized oxidized and inflammatory markers (CRP and IL-6), and partly restored total antioxidant status during 1-month treatment.

CONCLUSION:

This study demonstrates that hemodialysis with ERW administration may efficiently increase the H2O2- and HOCl-dependent antioxidant defense and reduce H2O2- and HOCl-induced oxidative stress.

 2003 Aug;64(2):704-14.
Reduced hemodialysis-induced oxidative stress in end-stage renal disease patients by electrolyzed reduced water.

Author information

1
Department of Family Medicine, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan.

Electrolysed-reduced water dialysate improves T-cell damage in end-stage renal disease patients with chronic haemodialysis

BACKGROUND:

T-cell damage by increased oxidative stress in end-stage renal disease (ESRD) patients undergoing chronic haemodialysis (HD) led to the increased T-cell apoptosis and the alteration of surface markers and Th1/Th2 ratio in CD4(+) T lymphocytes. Antioxidant electrolysed-reduced water (ERW) /alkaline ionized water was used as the dialysate in end-stage renal disease  ESRD patients undergoing  chronic haemodialys HD to test for improved oxidative stress-related T-cell apoptosis, alterations of surface markers and intracellular cytokine profile.

METHODS:

We evaluated apoptosis formation by annexin V, CD25-related surface markers, and cytokine ratio of Th1/Th2 in CD4(+) T lymphocytes and Tc1/Tc2 in CD8(+) T lymphocytes of 42  end-stage renal disease ESRD patients haemodialysed with electrolysed reduced water /alkaline ionized water ERW for 1 year.

RESULTS:

In comparison to 12 healthy individuals, the  end-stage renal disease ESRD patients had more T-cell apoptosis and less CD3(+), CD4(+) and CD8(+) T cells and CD25/CD69/CD94/CD3(+) phenotypes at baseline. Lower intracellular IL-2 and IFN-gamma levels in the Th1/CD4(+) and Tc1/CD8(+) cells and higher intracellular IL-4, IL-6 and IL-10 levels in the Th2/CD4(+) and Tc2/CD8(+) cells were also noted in the  end-stage renal disease ESRD patients.

After a 1-year ERW/alkaline ionized water  treatment, the patients had a decrease in T-cell apoptosis and increases in CD3(+), CD4(+) and CD8(+) cell numbers and CD25/CD69/CD94/CD3(+) phenotypes in the T cells. The intracellular IL-2 and IFN-gamma levels in the Th1/Tc1 cells significantly (P < 0.05) increased and the intracellular IL-4, IL-6 and IL-10 levels in the Th2/Tc2 cells decreased. Furthermore, the Th1/Th2 and Tc1/Tc2 cytokine ratios were improved toward a normal status.

CONCLUSION:

One-year ERW /alkaline ionized water treatment effectively ameliorated T-cell apoptosis, altered CD25-related surface markers and intracellular cytokine profile in the haemodialysis HD patients.

PMID: 20190245
DOI: 10.1093/ndt/gfq082
 2010 Aug;25(8):2730-7. doi: 10.1093/ndt/gfq082. Epub 2010 Feb 26.
Electrolysed-reduced water dialysate improves T-cell damage in end-stage renal disease patients with chronic haemodialysis.
1
Department of Family Medicine, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan.

Alkaline ionized water improves exercise-induced metabolic acidosis and enhances anaerobic exercise performance in combat sport athletes

note: this article may be useful to cancer patients as it is well known that most cancer cells use anaerobic glycolysis to produce ATP energy and excrete lactic acid  
Abstract

Hydration is one of the most significant issues for combat sports as athletes often use water restriction for quick weight loss before competition. It appears that alkaline water can be an effective alternative to sodium bicarbonate in preventing the effects of exercise-induced metabolic acidosis. Therefore, the main aim of the present study was to investigate, in a double blind, placebo controlled randomized study, the impact of mineral-based highly alkaline water on acid-base balance, hydration status, and anaerobic capacity. Sixteen well trained combat sport athletes (n = 16), were randomly divided into two groups; the experimental group (EG; n = 8), which ingested highly alkaline ionized water for three weeks, and the control group (CG; n = 8), which received regular table water. Anaerobic performance was evaluated by two double 30 s Wingate tests for lower and upper limbs, respectively, with a passive rest interval of 3 minutes between the bouts of exercise. Fingertip capillary blood samples for the assessment of lactate concentration were drawn at rest and during the 3rd min of recovery. In addition, acid-base equilibrium and electrolyte status were evaluated. Urine samples were evaluated for specific gravity and pH. The results indicate that drinking alkalized ionized water enhances hydration, improves acid-base balance and anaerobic exercise performance.

Introduction

Despite numerous scientific data, there is still no conclusive answer regarding what and how much we should drink to optimize sports performance. Until the middle of the 20th century, the recommendation was to avoid drinking to optimize performance. The first drinking guidelines were introduced by the ACSM to avoid heat stress in 1975, while hydration and performance were first addressed only in 1996 []. At that time, athletes were encouraged to drink the maximum amount of fluids during exercise that could be tolerated without gastrointestinal discomfort and up to the rate lost through sweating. Depending on the type of exercise and the environment, volumes from 0.6 to 1.2 L per hour were recommended. These drinking guidelines have been questioned recently, and other issues such as over hydration and hyponatremia have been addressed [].

The inconsistency of the results regarding hydration and sports performance arise from differences in experimental protocols. In studies in which dehydration develops during exercise, fluid loss of up to 4% body mass does not compromise performance, while in studies that induced dehydration prior to exercise, performance impairments have been observed after dehydration as low as 1–2% body mass []. Several comprehensive reviews on the influence of dehydration on muscle endurance, strength, anaerobic capacity, jumping performance and skill performance in team sport games have revealed negative effects of dehydration ≥ 2% body mass []. Hydration is one of the most significant issues for combat sports, as athletes often use water restriction for quick weight loss before competition. During tournaments lasting several hours, combat sport athletes sweat immensely and increase their core temperature affecting muscle strength, reducing motor cortex activation, peripheral stimulus as well as the speed of reaction and power output [].

Considering the vast amounts of fluids used during exercise, water seems to be the most often form of hydration. Water comes in different forms, with specific properties depending on its mineral content. The pH of water, as well as the proportions between SO42- and HCO3 determines hydration status and other therapeutic properties []. Drinking hydrogen rich water in human nutrition is a rather new concept, and it is recently suggested for medical purposes and hydration during exercise []. Alkaline ionized water is being marketed as a nutritional aid for the general public for acidity-lowering, antioxidant, and antiaging properties. Some of the animal and human research has confirmed its effectiveness as an alkalizing agent in the treatment of metabolic acidosis []. However, metabolic acidosis that occurs during high intensity exercise is a distinct form of metabolic alteration, when cells are forced to rely on anaerobic ATP turnover that leads to proton release and a decrease in blood pH that can impair performance [].

Anaerobic exercise metabolism leads to the production of lactic acid in the working muscles. Part of the produced lactic acid is released to the blood, reducing blood pH, and disturbing acid—base balance. Several studies have provided evidence that hydrogen ions are released from the muscles in excess of lactate after intense exercise []. Two mechanisms have been proposed to explain this phenomenon. It seems that hydrogen ions are released both by a sodium-hydrogen ion exchanger and by a lactic acid transporter []. Since red blood cells have a higher buffering capacity than blood plasma, the lactate generated during exercise largely remains in the plasma while hydrogen ions are transferred to the red blood cells and buffered by hemoglobin []. One of the objectives of training and supplementation in high intensity anaerobic sports disciplines is to increase the buffering capacity of the blood and tissues []. The use of sodium bicarbonate has proven effective in speed endurance and strength endurance sports, yet its use has been limited due to the possibility of gastrointestinal distress, metabolic alkalosis, and even edema due to sodium overload []. It appears that alkaline water can be an effective alternative to sodium bicarbonate in preventing exercise-induced metabolic acidosis []. Contrary to bicarbonate, alkaline water can be used on an everyday basis and has no known side effects. However, there are only few cross-sectional or longitudinal studies on the impact of alkaline water ingestion in combat sport athletes. Therefore, the main objective of the current study was to investigate in a double blind, placebo controlled randomized study, the impact of mineral-based highly alkaline water on acid-base balance, hydration status, and anaerobic capacity in experienced combat sport athletes subjected to a very intense exercise protocol.

Materials and methods

Subjects

Sixteen very well-trained males, who trained and competed in combat sports for at least 7.6 years, participated in the study. The athletes constituted a homogenous group in regard to age (average age of 22.3 ± 0.5 years), somatic characteristics, as well as aerobic and anaerobic performance (Table 1). The subjects (n = 16) were randomly divided into two groups, the experimental group (EG; n = 8), which received highly alkaline ionized water, and the control group (CG; n = 8), which was hydrated with table water. All subjects had valid medical examinations and showed no contraindications to participate in the study. The athletes were informed verbally and in writing of the experimental protocol, the possibility to withdraw at any stage of the experiment, and gave their written consent for participation. The study was approved by the Research Ethics Committee of the Academy of Physical Education in Katowice, Poland.

Table 1

Characteristics of the study participants.
Variables Experimental Group
(n = 8)
Control Group
(n = 8)
Age (yrs.) 22.7±3.2 22.4 ± 2.8
Height (cm) 181.2±2.1 178.3±4.9
Body mass (kg) 81.8±3.2 79.2 ±2.6
FM (%) 10.2±2.1 10.8±2.4
Wt—upper limbs (J/kg) 138±14 136±19
Wt—lower limbs (J/kg) 276±04 283±26
Pmax–lower limbs (W/kg)
Pmax–upper limbs (W/kg)
19.8±0.9
8.9±1.1
20.2±1.6
8.7±0.4
VO2max (ml/kg/min) 64.7±2.8 62.6±3.2

Diet and hydration protocol

Energy intake, as well as macro and micronutrient an intake of all subjects was determined by the 24 h nutrition recall 3 weeks before the study was initiated. The participants were placed on an isocaloric (3455 ± 436 kcal/d) mixed diet (55% carbohydrates, 20% protein, 25% fat) prior and during the investigation. The pre-trial meals were standardized for energy intake (600 kcal) and consisted of carbohydrate (70%), fat (20%) and protein (10%). During the experiment, and 3 weeks before the commencement of the study, the participants did not take any medications or supplements. Throughout the experiment water intake was individualized based on the recommendation of the National Athletic Trainers Association and averaged 2.6–3.2 L per day. In our study we used water which had a pH of 9.13 which is highly alkaline compared to other commercially available products. The water ingested during the experiment contained 840 mg/dm3 of permanent ingredients, and was classified as medium mineral content. The bicarbonate ion HCO3 (357.8 mg/dm3) and carbonate ion CO32- (163.5 mg/dm3) consisted the dominant anions. Sodium (Na+ 254.55 mg/dm3) dominated among cations. The water contained bicarbonate, carbonate-sodium (HCO3, CO3Na+). The chemical properties of both types of water used in the experiment (alkaline and table water) are presented in Table 2.

Table 2

Chemical properties of water used in the study.
Variable Measurement Unit Alkaline Water Table Water
pH pH 9.13 ± 0.04 5.00 ± 0.08
CO32- mg/dm3 163.5 ± 6.3 14.98 ± 0.66
HCO3 mg/dm3 357.8 ± 6.14 3.62 ± 0.12
Cl mg/dm3 26.4 ± 2.3 0.41 ± 0.03
SO42- mg/dm3 7.81± 1.2 1.60 ± 0.09
Na+ mg/dm3 254.55 ± 7.1 1.21 ± 0.05
K+ mg/dm3 0.91 ± 0.04 0.30 ± 0.03
Ca2+ mg/dm3 10.00 ± 1.6 1.21 ± 0.05
Mg2+ mg/dm3 0.37 ± 0.03 0.40 ± 0.04

Note: Data shows mean values ± SD of three analysis of each type of water

Study protocol

The experiment lasted 3 weeks, during which two series of laboratory analyses were performed. The tests were carried out at baseline and after three weeks of hydration with alkaline or table water. The study was conducted during the preparatory period of the annual training cycle, when a high volume of work dominated the daily training loads. The participants refrained from exercise for 2 days before testing to minimize the effect of fatigue.

The subjects underwent medical examinations and somatic measurements. Body composition was evaluated in the morning, between 8.00 and 8.30 am. The day before, the participants had the last meal at 20.00. They reported to the laboratory after an overnight fast, refraining from exercise for 48h. The measurements of body mass were performed on a medical scale with a precision of 0.1 Kg. Body composition was evaluated using the electrical impedance technique (Inbody 720, Biospace Co., Japan). Anaerobic performance was evaluated by a two double 30-second Wingate test protocol for lower and upper limbs respectively, with a passive rest interval of 3 minutes between the bouts of exercise. The test was preceded by a 5 min warm-up with a resistance of 100 W and cadence within 70–80 rpm for lower limbs and 40 W and 50–60 rpm for the upper limbs. Following the warm-up, the test trial started, in which the objective was to reach the highest cadence in the shortest possible time, and to maintain it throughout the test. The lower limb Wingate protocol was performed on an Excalibur Sport ergocycle with a resistance of 0.8 Nm·Kg-1 (Lode BV, Groningen, Netherland). The upper body Wingate test was carried out on a rotator with a flying start with a load of 0.45 Nm·Kg-1 (Brachumera Sport, Lode, Netherland). Each subject completed 4 test trials with incomplete rest intervals. The variables of peak power–Pmax (W/Kg) and total work performed–Wt (J/Kg), were registered and calculated by the Lode Ergometer Manager (LEM, software package, Netherland).

Biochemical assays

To determine lactate concentration (LA), acid-base equilibrium and electrolyte status the following variables were evaluated: LA (mmol/L), blood pH, pCO2 (mmHg), pO2 (mmHg), HCO3- act (mmol/L), HCO3-std, (mmol/L), BE (mmol/L), O2SAT (mmol/L), ctCO2 (mmol/L), Na+ (mmol/L), and K+ (mmol/L). The measurements were performed on fingertip capillary blood samples at rest and after 3 minutes of recovery. Determination of LA was based on an enzymatic method (Biosen C-line Clinic, EKF-diagnostic GmbH, Barleben, Germany). The remaining variables were measured using a Blood Gas Analyzer GEM 3500 (GEM Premier 3500, Germany).

Urine samples were taken at rest, after an overnight fast, at baseline and at the conclusion of the investigation. They were placed in a plastic container and mixed with 5 ml/L of 5% solution of isopropyl alcohol and thymol for preservation. Urine samples were assayed for the presence of blood and proteins. Specific gravity was determined using the Atago Digital refractometer (Atago Digital, USA). Urine pH was determined based on the standardized Mettler Toledo potentiometer (Mettler Toledo, Germany).

Statistical analysis

The Shapiro-Wilk, Levene and Mauchly´s tests were used to verify the normality, homogeneity and sphericity of the sample’s data variances, respectively. Verifications of the differences between analyzed variables before and after water supplementation and between the EG and CG were performed using ANOVA with repeated measures. Effect sizes (Cohen’s d) were reported where appropriate. Parametric effect sizes were defined as large for d > 0.8, as moderate between 0.8 and 0.5, and as small for < 0.5 (Cohen 1988; Maszczyk et al., 2014, 2016). Statistical significance was set at p<0.05. All statistical analyses were performed using Statistica 9.1 and Microsoft Office, and were presented as means with standard deviations.

Results

All participants completed the described testing protocol. All procedures were carried out in identical environmental conditions with an air temperature of 19.2°C and humidity of 58% (Carl Roth hydrometer, Germany).

The repeated measures ANOVA between the experimental and control group and between the baseline and post-intervention period (3 weeks of alkaline and table water ingestion) revealed statistically significant differences for thirteen variables (Table 3).

Table 3

Statistically significant differences between the experimental and control groups at baseline and after 3 weeks of intervention (alkaline vs table water).
Variables d p F
Wingate Lower Limbs Average Power Exp. 0.884 0.001 21.161
Wingate Upper Limbs Average Power Exp. 0.587 0.011 8.528
Wingate UL Peak Power Exp. 0.501 0.026 6.228
Wingate LL Total Work Exp. 0.567 0.045 4.822
Wingate UL Total Work Exp. 0.522 0.011 8.459
LA rest 0.534 0.008 9.429
LA post exr 0.618 0.003 13.382
pH rest 0.834 0.001 120.159
HCO3 rest 0.844 0.001 109.250
HCO3 post exr 0.632 0.002 14.724
K+ post exr 0.501 0.040 5.154
Urine pH 0.589 0.017 7.298
SG 0.884 0.001 19.707

Note: d—effect size; p—statistical significance

F–value of analysis of variance function

Post-hoc tests revealed a statistically significant increase in mean power when comparing the values (7.98 J/kg to 9.38 J/kg with p = 0.001) at baseline vs. at the conclusion of the study in the experimental group supplemented with alkaline water. In contrast, the control group which received table water did not reveal any statistically significant results.

Similar changes were observed for Upper Limb Average Power (from 4.32 J/kg to 5.11 J/kg with p = 0.011) and Upper Limb Peak Power (from 7.90 J/kg to 8.91 J/kg with p = 0.025) in the experimental group. The post-hoc tests also showed statistically significant increases in values for Lower Limb Total Work (from 276.04 J/kg to 292.96 J/kg with p = 0.012) and Upper Limb Total Work (from 138.15 J/kg to 156.37 J/kg with p = 0.012) when baseline and post intervention values were compared. The changes in the control group were not statistically significant. These results are presented in Fig 1.

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Differences between the control and experimental groups in total work of the lower and upper limbs (30s Wingate test) at baseline and after 3 weeks of alkaline or table water ingestion.

Note: * statistically significant values.

Post-hoc tests also revealed statistically significant decreases in LA concentration at rest (from 1.99 mmol/L to 1.30 mmol/L with p = 0.008), and a significant increase in post exercise LA concentration (from 19.09 mmol/L to 21.20 mmol/L with p = 0.003) in the experimental group ingesting alkaline water.

Additionally, a significant increase in blood pH at rest (from 7.36 to 7.44 with p = 0.001), HCO3 at rest (from 23.87 to 26.76 with p = 0.001), and HCO3 post exercise (from 12.90 to 13.88 with p = 0.002) were observed in the experimental group. The other significant changes occurred in the post exercise concentration of K+ (from 4.15 to 4.41 with p = 0.039), in urine pH (from 5.75 to 6.62 with p = 0.017), and a decrease in the value of SG (from 1.02 to 1.00 with p = 0.001), all in the experimental group supplemented with alkaline water.

Discussion

Acid-base equilibrium within the human body is tightly maintained through the blood and tissue buffering systems, the diffusion of carbon dioxide from the blood to the lungs via respiration, and the excretion of hydrogen ions from the blood to urine by the kidneys. These mechanisms also regulate acid-base balance following high intensity exercise. Metabolic acidosis is a consequence of exercise induced ionic changes in contracting muscles. Increased intramuscular acidity impairs muscle contractibility, significantly limiting high intensity exercise performance []. Importantly, acid-base equilibrium can be influenced by dietary supplementation.

In the present study, we investigated the effect of mineral-based alkaline water on acid-base balance, hydration status and anaerobic performance of competitive combat sport athletes. The study participants were experienced athletes (Table 1), capable of performing extreme anaerobic efforts. We have chosen such an approach for two reasons. First, it is well-documented that consumption of alkalizing water can have a significant effect on the hydration status, acid-base balance, urine and blood pH [], as well as Ca metabolism and bone resorption markers []. However, the majority of these research reports have been performed on sedentary individuals [] or on subjects with self-reported physical activity []. Second, alkalization by alkaline water has been mostly discussed in the context of dehydration and aerobic performance []. Therefore, our study is novel by including both well trained combat sport athletes and the use of an extremely intensive anaerobic exercise protocol.

Acid-base balance and hydration status

The exchange of ions, CO2, and water between the intracellular and extracellular compartments helps to restore acid-base balance following intensive exercise. There is sufficient data indicating that, supplements that modify the blood buffering system affect high-intensity exercise performance []. In humans, especially well trained athletes muscle pH may decrease from 7.0 at rest to values as low as 6.4–6.5 during exercise []. Ergogenic aids that help buffer protons attenuate changes in pH and enhance the muscle’s buffering capacity. This in turn allows for a greater amount of lactate to accumulate in the muscle during exercise.

The results of our study are in line with the available literature regarding the impact of alkaline water on blood and urine pH at rest []. However, novel results of the present research are related to the changes in HCO3- after exercise in athletes ingesting alkaline water. Bicarbonate-CO2 accounts for more than 90% of the plasma buffering capacity. Supplementation can increase bicarbonate concentration in the blood and its pH. Since bicarbonate concentration is much lower in the muscles (10 mmol/L) than in the blood (25 mmol/L), the low permeability of charged bicarbonate ions precludes any immediate effects on muscle acid-base status []. These results confirm the view that an appropriate hydration status is necessary for active bicarbonate ion transport.

Several lines of evidence support the negative impact of dehydration (>2% body mass) on muscle endurance, strength, and anaerobic performance []. On the other hand, literature data indicates that consumption of alkaline water following a dehydrating bout of cycling exercise was shown to rehydrate cyclists faster and more completely compared to table water. Following consumption of alkaline water, the cyclists demonstrated lower total urine output, their urine was more concentrated (i.e., with higher specific gravity), and the total blood protein concentration was lower, indicating improved hydration status [].

Our previous study revealed that the use of water with alkalizing properties exhibits a significant potential for hydration during anaerobic exercise []. The results of the present study confirm a decrease in urine specific gravity (from 1.02 to 1.00, with p = 0.001) and an increase in urine pH as the result of consumption of alkaline water. These results illustrate that the habitual consumption of highly alkaline water can markedly improve hydration status.

Anaerobic performance

The current investigation demonstrated a significant increase in anaerobic capacity (Wt−J/Kg) of athletes in the experimental group supplemented with alkaline water. The improvements in Wt following alkaline water consumption were influenced by positive changes in blood pH and bicarbonate. This phenomenon could be explained by the ergogenic effects of high alkalization and mineral ingredients.

High intensity exercise in which anaerobic glycolysis provides ATP for muscle contraction leads to an equal production of lactate and hydrogen ions. Most of the released hydrogen ions are buffered; however, a small portion (~0.001%) that remains in the cytosol causes a decrease in muscle pH and an impairment of exercise. Lactate efflux [] and its oxidation are accompanied by a similar removal of hydrogen ions. The results of the current study demonstrated a statistically significant decrease in lactate concentration at rest (from 1.99 mmol/L to 1.30 mmol/L, p = 0.008), and a significant increase post exercise (from 19.09 mmol/L to 21.20 mmol/L, p = 0.003) when compared to the baseline levels with the values recorded at the end of alkaline water supplementation. The extremely intense 4 x 30s upper/lower limb Wingate test protocol employed in our study, with only short rest intervals between each bout of exercise, was a likely reason that less of the total lactate produced in the muscles was transported to the blood [].

Muscle blood flow determines lactate efflux from the muscle [], and is dependent on the activity of lactate transport proteins [], the extracellular buffering capacity [], and the extracellular lactate concentration []. Thus, our results on lactate concentration are in agreement with the view that anaerobic performance (i.e., Wt−J/Kg, WAvr−J/Kg) depends on counter-regulatory variables. Indeed, we demonstrated that changes in resting blood pH and HCO3 significantly improved anaerobic performance.

Another variable that can affect anaerobic performance includes blood viscosity. Weidmann et al. (2016) showed that the intake of highly alkaline water decreased blood viscosity by 6.30%, compared to table water (3.36%) in 100 recreationally active female and male subjects. Therefore, it may be possible that the excess of metabolic end-products (namely, H+ and Pi), which disturb cellular homeostasis and muscle contraction, are more effectively transported. The available literature data does not specify clearly which components of buffering capacity are altered by the above changes. It must be indicated, that there are several methods available to determine muscle buffering capacity. Due to the methodological complexity, none of these methods are free from criticism. In most studies buffering capacity has been determined in vitro by titration, which does not include trans-membrane transport of acid-base substances or dynamic buffering by biochemical processes occurring in vivo [].

Most studies show a documented ergogenic effect of bicarbonate loading during exhaustive exercise lasting 1–7 min, when anaerobic glycolysis plays a major role in energy provision []. The rationale for the ergogenic effect of bicarbonate is that the increase in extracellular pH and bicarbonate will enhance the efflux of lactate and H+ from muscle. There is also evidence that the ergogenic effect of bicarbonate is more pronounced during repeated sprints than during sustained exercise [].

Different strategies used for improving buffering capacity of tissues and blood do not allow for a direct comparison. Despite this, there appears to exist an ergogenic effect in response to NaHCO3, what may explain the large effect size noted by Tobias et al. []. In our research we obtained large effect sizes with regards to 4 variables (Average power of the lower limbs, resting HCO3, resting blood pH and urine SG).

Conclusions

The results of the present study indicate that drinking alkalized water improves hydration status, acid-base balance, and high intensity anaerobic exercise performance. It appears that both greater muscle buffering capacity and enhanced removal of protons, resulting in increased glycolytic ATP production, may be responsible for these effects. Considering the energy demands and the intense sweat rate of combat sport athletes, the authors recommend the daily intake of 3–4 L of highly alkaline mineralized water to improve hydration and anaerobic performance during training and competition.

Supporting information

S1 Table

Data for Fig 1.

(XLSX)

S2 Table

Stress test data.

(XLSX)

S3 Table

Water data.

(XLSX)

Acknowledgments

This work was supported by the Ministry of Science and Higher Education of Poland under Grant NRSA3 03953 and NRSA4 040 54.

Funding Statement

This work was supported by the Ministry of Science and Higher Education of Poland under Grant NRSA3 03953 and NRSA4 040 54.

Data Availability

All relevant data are within the paper and its Supporting Information files.

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PLoS One View this Article Submit to PLoS Get E-mail Alerts Contact Us Public Library of Science (PLoS)
. 2018; 13(11): e0205708.
Published online 2018 Nov 19. doi: 10.1371/journal.pone.0205708
PMCID: PMC6242303
PMID: 30452459
Alkaline ionized water improves exercise-induced metabolic acidosis and enhances anaerobic exercise performance in combat sport athletes
Jakub ChyckiConceptualizationInvestigationMethodologyWriting – original draft,1,* Anna KurylasData curationMethodologyProject administration,1 Adam MaszczykData curationValidationVisualization,2Artur GolasData curationFormal analysis,1 and Adam ZajacConceptualizationInvestigationMethodologyWriting – original draft1
Michal Toborek, Editor
This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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12. Watanabe T, Pan I, Fukuda Y, Murasugi E, Kamata H, Uwatoko K. Influences of alkaline ionized water on milk yield, body weight of offspring and perinatal dam in ratsJournal of Toxicological Sciences 1998; 23, 365–371. [PubMed]
13. Robergs RA, Ghiasvand F, Parker D. Biochemistry of exercise-induced metabolic acidosisAmerican Journal of Physiology, Regulatory, Integrative and Comparative Physiology 2004; 287, R502–516. 10.1152/ajpregu.00114.2004 [PubMed]
14. Bangsbo J, Johansen L, Graham T, Saltin B. Lactate and H+ effluxes from human skeletal muscles during intense dynamic exerciseJournal of Physiology 1993; 422, 539–559. [PMC free article] [PubMed]
15. Juel C. Lactate-proton cotransport in skeletal musclePhysiol Rev 1997; 77:321–58. 10.1152/physrev.1997.77.2.321 [PubMed]
16. Medbo JI, Hanem S, Noddeland H, Jebens E. Arterio-venous differences of blood acid-base status and plasma sodium caused by intense bicyclingActa Physiol Scand 2000; 168, 311–326. 10.1046/j.1365-201x.2000.00650.x [PubMed]
17. Putman CT, Jones NL, Heigenhauser GJF. Effects of short-term training on plasma acid-base balance during incremental exercise in manJ Physiol 2003; 550, 585–603. 10.1113/jphysiol.2003.039743[PMC free article] [PubMed]
18. McNaughton LR, Siegler J, Midgley A. Ergogenic effects of sodium bicarbonateCurr Sports Med Rep2008;7 (4):230:6. 10.1249/JSR.0b013e31817ef530 [PubMed]
19. Kurylas A, Zajac T, Chycki J, Maszczyk A. Zajac A. Anaerobic Performance and Acid-Base Balance in Basketball Players after the Consumption of Highly Alkaline WaterInt J Food and Nutr Sci2018;5(1):134–9.
20. Gledhill N. Bicarbonate ingestion and anaerobic performanceSports Med 1984; 1: 177–80. 10.2165/00007256-198401030-00001 [PubMed]
21. Wynn E, Raetz E, Burckhardt P. The composition of mineral waters sourced from Europe and North America in respect to bone health: composition of mineral water optimal boneBr J Nut 2009; 101:1195–1199. [PubMed]
22. Santaka S, Takeki H, Kiichiro T. Advanced research on the health benefit of reduced waterTrends Food Sc and Technol; 2012, 23,(2): 124–131.
23. Amelia J, Carr AJ, Will G, Hopkins C, Gore J. Effects of Acute Alkalosis and Acidosis on PerformanceSport Med 2011; 1; 41(10). [PubMed]
24. Sahlin K. Intracellular pH and energy metabolism in skeletal muscle, with special reference to exerciseActa Physiol Scand Suppl 1978; 455:1–56. [PubMed]
25. Weidman J, Holsworth RE, Brossman B, Cho JD, Cyr J, Fridman G. Effect of electrolyzed high-pH alkaline water on blood viscosity in healthy adultsJ Int Soc Sports Nutr 2016; 13:45 10.1186/s12970-016-0153-8[PMC free article] [PubMed]
26. Armstrong LE, Ganio MS, Klau JF, Johnson EC, Casa DJ, Maresh CM. Novel hydration assessment techniques employing thirst and a water intake challenge in healthy menAppl. Physiol Nutr Metab 2014; 39; 138–144. 10.1139/apnm-2012-0369 [PubMed]
27. Katz A, Broberg S, Sahlin K. Muscle ammonia and amino acid metabolism during dynamic exercise in manClin Physiol 1986; 6:365–79. [PubMed]
28. Harris RC, Hultman E, Nordesjo LO. Glycogen, glycolytic intermediates and high-energy phosphates determined in biopsy samples of musculus quadriceps femoris of men at rest. Methods and variance of valuesScan J Clin Lab Invest 1974; 33:109–20. [PubMed]
29. Bonen A, McCullagh KJ, Putman CT. Short-term training increases human muscle MCT1 and femoral venous lactate in relation to muscle lactateAm J Physiol 1998; 274:E102–7. [PubMed]
30. Carr AJ, Hopkins WG, Gore CJ. Effect of acute alkalosis and acidosis on performance: a meta-analysisSports Med. 2011, 41:801–14. 10.2165/11591440-000000000-00000 [PubMed]
31. Edge J, Bishop D, Goodman C. The effects of training intensity on muscle buffer capacity in femalesEur J Appl Physiol, 2006, 96:97 10.1007/s00421-005-0068-6 [PubMed]
32. Linderman JK, Gosselink KL. The effects of sodium bicarbonate ingestion on exercise performanceSports Med 1994, 18:75–80. 10.2165/00007256-199418020-00001 [PubMed]
33. Tobias G, Benatti FB, de Salles Painelli V, Roschel H, Gualano B, Sale C, Harris RC, Lancha, AH, Artioli GG. Additive effects of beta-alanine and sodium bicarbonate on upper-body intermittent performanceAmino Acids 2013, 45:30917. [PMC free article] [PubMed]

Articles from PLoS ONE are provided here courtesy of Public Library of Science

 

Alkaline Ionized Water/ electrolyzed reduced water inhibits tumor angiogenesis

Alkaline Ionized Water / electrolyzed reduced water(ERW /AIW ) inhibits tumor angiogenesis

The present study demonstrated that Electrolyzed Reduced Water (aka ionized alkaline water)  down-regulated Vascular endothelial growth factor VEGF gene transcription and protein secretion through inactivation of ERK.

Thus this study demostrated that alkaline ionized water inhibits tumor angiogenesis and can be safely & easily used as a complementary / integrative cancer treatment.

 
 

Vascular endothelial growth factor (VEGF) is a key mediator of tumor angiogenesis. Tumor cells are exposed to higher oxidative stress compared to normal cells. Numerous reports have demonstrated that the intracellular redox (oxidation/reduction) state is closely associated with the pattern of VEGF expression.

Electrolyzed reduced water (ERW) aka Alkaline Ionized Water produced near the cathode during the electrolysis of water scavenged intracellular H(2)O(2) and decreased the release of H(2)O(2) from a human lung adenocarcinoma cell line, A549, and down-regulated both VEGF transcription and protein secretion in a time-dependent manner.

To investigate the signal transduction pathway involved in regulating VEGF expression, mitogen-activated kinase (MAPK) specific inhibitors, SB203580 (p38 MAPK inhibitor), PD98059 (ERK1/2 inhibitor) and JNKi (c-Jun N-terminal protein kinase inhibitor) were applied.

The results showed that only PD98059 blocks VEGF expression, suggesting an important role for ERK1/2 in regulating VEGF expression in A549 cells. As well, Alkaline Ionized Water aka Electrolyzed Reduced Water inhibited the activation of extracellular signal-regulated kinase (ERK) in a time-dependent manner. Co-culture experiments to analyze in vitro tubule formation assay revealed that A549 cell-derived conditioned medium significantly stimulated the formation of vascular tubules in all analyzed parameters; tubule total area, tubule junction, number of tubules, and total tubule length. Electrolyzed Reduced Water /Alkaline Ionized Water counteracted the effect of A549 cell-conditioned medium and decreased total tube length (p<0.01).

 
 

https://www.jstage.jst.go.jp/article/bpb/31/1/31_1_19/_pdf

PMID:18175936
https://www.ncbi.nlm.nih.gov/pubmed/18175936/

 

The Diatomic Molecular Hydrogen H2 Infusion Advantage of a water ionizer

The Diatomic Molecular Hydrogen  H2 Infusion Advantage of a water ionizer

What makes AlkaViva H2 water ionizers a very Smart Choice?!

alkaviva h2 water ionizers
alkaviva h2 water ionizers

 

AlkaViva Vesta H2 water ionizer & purifier certifications
AlkaViva  H2 water ionizer & purifier certifications
Water ionizer performance used to be entirely focused on pH/ORP and the electrodes.  
 
The market focus for water ionizers is now on diatomic molecular hydrogen H2 water infusion/generation  performance.
The water cell – the heart and engine of the water ionizer – has two components: electrodes and (ion exchange) membranes.
Diatomic molecular hydrogen- H2 water Infusion Technology is based on the fact that water ionization cell membranes are as critical as the electrodes.
AlkaViva water ionization cell membranes are made in-house(NOT from outside sources) and are ultrasonically pressed, rather than bonded with chemicals. This provides you with a distinctly superior water ionization cell membrane that is designed to work specifically with AlkaViva SMART DESIGN electrodes, giving unmatched water ionization performance.
When you put together AlkaViva advanced SmartDesign electrodes to AlkaViva ultrasonically pressed  water ionization cell membranes, the result is a great level of diatomic molecular hydrogen H2 dizolved in water
 Technology and better diatomic molecular hydrogen  H2 performance(meaning more molecular hydrogen H2 dizolved in ionized alkaline water). This is especially so at the better tasting lower levels of pH(7 up to 10)
Diatomic molecular hydrogen H2 infusion/generation Test Results for AlkaViva H2 water ionizers and purifiers  >>> Click here.

Benefits of Diatomic molecular Hydrogen H2

Molecular Hydrogen is the lightest and simplest element making it easy to absorb by your body. Over 500 studies show that biatomic molecular hydrogen or Hhas a therapeutic benefit in 140 health conditions and disease models.

beneficii apa hidrogenata
benefits of molecular hydrogen water

H2_diatomicHydrogenWaterbenefits1

 
 
  • Increase in Energy – Adenosine Triphosphate (ATP) is the fuel that powers your live human cells during physical activity. Drinking diatomic molecular  hydrogen H2 infused UltraWater helps maintain the high ATP production needed during exercise – providing optimal strength, endurance and recovery.
  • Reduced Lactic acid (Muscle Fatigue, Cachexia in cancer patients)  – When you exercise, your lactic acid increases. Same happens if you are a cancer patient and eat sugar. Lactic acid buildup leads to fatigue, muscle damage, decreased endurance, reduced performance, and poor training results and even cachexia in cancer . Peer-reviewed research on athletes shows that diatomic molecular hydrogen decreases lactic acid levels.
  • Improves your Hydration – When diatomic molecular hydrogen H2 molecules combine with and neutralize damaging oxygen radicals, they are transformed into water (H2O) – increasing your cellular hydration. The water ionization also creates a light, silky-smooth tasting water that is easy to drink(ionized water  penetrates cells better).
  • Incredible Antioxidant Power – Exercise requires more oxygen than most activities. Increases in oxygen can produce free radicals, leading to chain reactions and eventually cell damage. Oxidation is literally the aging process while antioxidants prevent or slow down the oxidative damage. Most antioxidants neutralize free bad radicals, but they can also neutralize the good ones that your body needs. Molecular hydrogen selectively targets only the damaging oxygen radicals, leaving behind the good radicals. This makes it a superior antioxidant.

Alkaline Ionized Water ( pH, ORP ) and Diatomic Hydrogen Water

Alkaline Ionized Water , pH, ORP and Diatomic Hydrogen Water

 

The ability to produce high concentrations of molecular hydrogen at a pH of around 9.5 is probably the most important thing to consider when choosing a water ionizer.

Alkaline ionized water(AIO) or Electrolisys Reduced Water (ERW) is most efficiently produced by using an electric water ionizer. Alkaline ionized water (also molecular hydrogen water) is marketed by many names. Until recently this water was commonly referred to scientifically as Electrolyzed Reduced Water (ERW).

Now, scientists are often referring to it as Molecular Hydrogen Water. This is because research (especially in the past 10 years) has shown that the dissolved molecular hydrogen gas (H2), present in water created by electric water ionizers, is what is mainly responsible for its many benefits. Perhaps the most accurate name is electrolytically-produced, hydrogen-enriched, alkaline water.

Why  molecular hydrogen H2 (water)
is good for  your health regimen?

 H2 molecular hydrogen (water) is the Master Antioxidant
Molecular hydrogen is the smallest element and lightest molecule so it easily diffuses into subcellular compartments scavenging dangerous oxygen radicals and so protects DNA and RNA from oxidative stress.

 H2  Molecular hydrogen  Activates your Body’s own Powerful Enzymes
Molecular hydrogen H2 triggers the activation of additional antioxidant enzymes such as glutathione and other cell-protective proteins.

Research Suggests Therapeutic Benefit of Molecular hydrogen in Over 130 Disease Models
Over 500 peer-reviewed scientific articles indicate this fact. Drinking H2-Molecular hydrogen saturated water produced the vast majority of the benefits observed.

 H2 Molecular hydrogen Can Favorably Alter Cell Metabolism, Signaling and Gene Expression
Research suggests that Molecular hydrogen H2 could improve cell signaling functions and provide anti-inflammatory, anti-allergic and anti-apoptotic (anti-cell death) effects.

H2Viva – the most powerful and proven molecular hydrogen.

The Benefits of Molecular hydrogen (water)

Due to the large amount of research, over the past ten years, on the effects of Molecular hydrogen H2 in water, we now know that the hydroxide ion (OH-) is NOT responsible for most of the positive effects observed when drinking alkaline ionized water. The active antioxidant in ionized water is dissolved molecular hydrogen (H2).

In 2010, a review article, published in “Free Radical Research” stated; “It is not an overestimate to say that hydrogen’s impact on therapeutic and preventative medicine could be enormous in the future”. Since that article was published there have been over 200 peer-reviewed articles published, that focus on about 80 different diseases models, and that conclude that molecular hydrogen (water) appears to have a beneficial effect.

Great news for AlkaViva water ionizers customers:

We have tested (using Reno city water as our source) ionized alkaline water from 2 AlkaViva water ionizers, the Vesta GL 988 water ionizer & purifier and Athena JS 205 water ionizer & purifier. Both consistently on demand produced molecular hydrogen H2 concentrations of around .6 ppm at a 9.5 pH. Higher levels can be also achieved by slowing dowm the water flow etc. This is higher than test results obtained from any other water ionizer.

We are also happy to announce we now have a new series of water ionizers with hydrogen infusion technology that include the latest innnovations  .

compare BEST water ionizers
compare BEST water ionizers

As you can see , the new AlkaViva H2 water ionizers can produce as much molecular hydrogen in alkaline ionized water as 1.6 ppm( up to saturation point!!!)

We compared the new AlkaViva water purifiers (2 filters) – ionizers  with  Hydrogen Infusion Technology H2. the water purifiers-ionizers(Melody II H2, Athena H2, Vesta H2) , water purifiers -ionizers with Double Reverse AutoCleanse System for electrode / water ionization plates  DARC2, water purifiers – ionizers with SMPS power source and AutoAdjust technology  (that  dynamically & real time varies the power applied to the electrodes according to the varying mineral content of the filtered water that enters the water ionization cell), water purifiers-ionisers with  SmartDesign electrodes (low power, small in size but energy effective),water  purifiers – ionizers with 2 water filters (a water prefilter  and water filter) , and water purifiers –  ionizers with the most recent AlkaViva technology: infusion of hydrogen  H2

AlkaViva H2 hydrogen infusion water ionizers compared(Melody H2, Athena H2, Vesta H2)

Water containing dissolved molecular hydrogen H2 neutralizes only the free radicals that are directly toxic to cells and do not have a biologically important cell signaling role. Therefore alkaline, ionized water, with a good saturation of hydrogen molecules. appears to be an ideal choice of antioxidant.

The reason why the right brand of electric water  ionizer is the most efficient way of producing H2 (hydrogen water) is because it produces, every time, consistent amounts of molecular hydrogen in the ionized alkaline water.

Non-electric water ionizers rely on magnesium in their water filters to make the molecular hydrogen water and the water filters need to remain emersed in water for a good while to get the levels of dissolved molecular hydrogen  Hthey advertise. They are therefore more like batch units that will give no molecular hydrogen H2 if used for more than a liter or two of alkalized ionized water at once.

Taking the benefits one step further, AlkaViva water ionizers are the only water ionizers to give more than basic water filtration of the input water. AlkaViva water filters are the only ones that are USA made with results certified by an independent EPA laboratory-see results for AlkaViva UltraWater filters here. Failure to clean input water from contaminants means that certain heavy metals, pharmaceuticals etc present in your drinking water can also be made more bio-available once water is ionized.

 

 

Background on (electric) Water Ionizers

In 1965 the Japanese Ministry of Health, Labor and Welfare (JMHLW) approved (electric) water ionizers as a medical substance generator which could help with gastrointestinal symptoms under the Pharmaceutical Affairs Law. Currently Japanese companies still get certified through the JMHLW. In Korea, the Korean FDA certifies water ionizers sold or manufactured in that country.

There have been numerous peer reviewed article published in the past 15 years on the wide-ranging benefits from drinking alkaline, ionized water from an electric water ionizer. In that time there has been no reports of any negative effects.

Water ionizers have been sold in Asia for about 35 years and it is estimated that about 1 in 8 households in Japan and 1 in 12 households in South Korea use an electric water ionizer. Electric water ionizers have proven over this period to be safe and efficient devices for delivering enhanced water(clean , alkalized & alkaline, mineral, antioxidant,  hydrogen rich etc).

AlkaViva is the exclusive western Agent for Jupiter Science/ Emco Tech & BionTech water ionizers. These are the largest manufacturers of electric water ionizers in Asia that supply water ionizers  to companies such as Samsung, Toyo, LG and Hyundai.

HOW ELECTRIC WATER IONIZERS WORK

Electric water ionizers produce alkaline ionized  water containing dissolved molecular hydrogen at the cathode (the negative electrode) and acidic ionized water at the anode (the positive electrode). 

Each electric water ionizer contains a water/electrolisys  cell with water ionization plates/electrodes. A small electrical current is applied to these water ionization plates/electrodes. Membranes are placed between the electrodes to keep the acid and alkaline ionized water streams from mixing.

Only electric water ionizers are capable of consistently producing alkaline ionized water on demand that contains significant amounts of dissolved molecular hydrogen.(H2) enriched water.

 

How water ionizer works

 

Figure 2. Schematic of how an electric water ionizer works. Tap water is filtered, a salt solution may be added for strong alkaline and acidic waters, electrolysis is performed and the various ionized waters(acidic & alkaline) are produced.

Electrolysis in a electric water ionizer requires conductive minerals/electrolites  to be present. In theory you can produce hydrogen molecules (H2 water) using pure water()  but that would require a lot more wattage per area of water ionization plates/electrodes than the small amount needed in an electric water ionizer. But this is not good for water ionization plates/electrodes  That is why AlkaViva sells a remineralizing water filter for use with almost pure water, such as that produced using a reverse osmosis water filtration unit. It is also beneficial to drink mineral rich water.

Four basic types of water are produced by an electric water ionizer (different brands produce variations on each type):
” Mildly alkaline ionized water for drinking
” Mildly acidic ionized water for topical use
” Strong alkaline ionized  water for cleaning
” Strong acidic ionized water for cleaning

Alkaline drinking water (from an electric water  ionizer) typically has a pH of 8 – 10 and a Oxidation-Reduction Potential (ORP) of -50 to -750 mV and a molecular hydrogen (H2) level of about .5 ppm. The higher/stronger the -ORP the higher the H2 but there is a level of PH above which the water may taste unpleasant and is not recommended – or necessary. Also, ionized alkaline water with PH>10 is not safe to drink for a long time

Acidic ionized water typically has a pH of 4 – 6 and a ORP of +350 – +750 mV. There is no molecular  H2 produced in the acidic ionized water and this acid ionized water is not used for drinking but has many other purposes . It is possible to create a sterilizing 2.5 – 3 pH acidic water  solution but this is not recommended as it can, over time, degrade the surface of the water ionizing plates/electrodes.

 

How Hydrogen Water is Created – using a Water Ionizer

The process of producing alkaline and acidic water is relatively simple (as well as dissolved molecular hidrogen in water):  The H+ ions (acid) are attracted to the negatively charged cathode where they are converted to molecular hydrogen (H2) according to the equation: 2e- + 2H+ –> H2. Because pH is the concentration of the H+ ions, and the amount of H+ ions are being decreased (converted to H2) the pH increases thus making the water alkaline.  (Note: pH is logarithmic, so a decrease in H+ concentration is an increase in pH.)

At the other electrode, the hydroxide (OH) ions are attracted to the positive anode where they are oxidized to form H+ ions. Because pH is a measurement of the concentration of H+ ions, and the amount of H+ ions is being increased, the pH decreases thus making the water acidic.  (Note: pH is logarithmic, so an increase in H+concentration is a decrease in pH.

 

At the anode, (acidic ionized water side) the H+ ions, or more accurately H30+ (hydronium) ions, are produced.

At the cathode, an equal concentration of base (hydroxide ions or OH-) is produced.

If the two are combined, there is no change in the pH of the water.

The OH- ion is attracted to the positive electrode (anode) where they are oxidized to form oxygen gas (O2) and hydrogen ions (H+). The OH- ion (hydroxide) is neither an antioxidant or an oxidizing agent. The hydroxide ion is not a reactive molecule – it contains stable paired electrons.

The hydroxide ion is a BASE, but it is not a biological antioxidant.

The H+ ion is then attracted to the negative electrode (cathode -alkaline ionized water side) and is reduced to a hydrogen atom which immediately reacts with another H+ to form H2 – molecular hydrogen gas.

The decrease in H+ ions  results in a more alkaline water pH . Since there are more H+ ions (as hydronium ions) at the anode, the pH is acidic.

In other words, as you increase the pH, the H3O concentration decreases by the same amount that the OH- concentration increases. A 1-fold pH increase or decrease is a 10-fold change in the H3O+ concentration; changing the pH by 3 results in a 1,000-fold change in the H30+ concentration.

The actual diatomic molecular hydrogen produced and the pH and ORP vary due to the water ionizer used and the mineral content of the source water.

The ability to produce high concentrations of molecular hydrogen at a pH of around 9.5 is probably the most important thing to consider when choosing a water ionizer.

ORP

In ionized water ORP reflects the difference between the presence of dissolved molecular hydrogen H2and the concentration of H+. It measures the capacity of a solution to either release or accept electrons from chemical reactions. Oxidation is the loss of electrons. Reduction is GAINING electrons to become stable .

You can create a negative ORP by decreasing H+ (raising the pH) and/or increasing the dissolved molecular hydrogen concentration. You can make the ORP positive by increasing the H+ concentration (lowering the pH) and/or decreasing the dissolved molecular hydrogen concentration. Ideally it is best not to drink water with a positive ORP because it causes the body to reduce it at the expense of consuming electrical energy from the cell membrane. Tap water and most bottled waters have a positive ORP.

Having a negative ORP does NOT make ionized alkaline water an antioxidant.

The concentration of H2 is the determining factor of antioxidant power of alkaline ionized water .

Negative ORP is a general indicator of the presence of dissolved molecular hydrogen H2 (the actual antioxidant in alkaline ionized water) but it does not accurately measure the concentration. Because  water’s pH plays a large role in ORP, you can have one glass of ionized alkaline water with an ORP of -800 mV and another with an ORP of -400 mV but because of the differences in pH the second glass can have more molecular hydrogen than the first.

Also once the pH is above 9.5, ORP is an invalid measurement of H2.

The ability to produce high concentrations of molecular hydrogen at a pH of 9.5 is the most important thing to consider when choosing a water ionizer.

A negative Oxidation-Reduction Potential (-ORP) is indicative of the presence of molecular hydrogen, but it is NOT a measurement of the concentration.

The Importance of ORP

  • A high positive ORP (+ORP) kills pathogens by stealing electrons from the bacteria’s DNA, cell membranes and proteins.
  • The high ORP (+ORP) of electrolyzed oxidizing acidic ionized water makes it an effective way to kill bacteria and viruses.
  • Oxygen has a high ORP and can damage DNA and proteins.
  • Molecular hydrogen (H2) has a very low ORP (-ORP) and is thus a reducing agent or antioxidant.
  • Chlorine is added to tap water to kill bacteria because it has a high positive ORP.
  • The ORP of the internal environment of a healthy person is always on the reductive side (negative). Human saliva and mother’s milk has an ORP of -70 mv, with some redox couples below -350 mV.
  • Drinking water with a positive ORP causes the body to reduce it at the expense of consuming electrical energy from human cell membranes. Tap water, bottled water, rain water, RO water, have a positive ORP; most between 200-400 mV and as high as 500-600 mV.
  • Optimal drinking water has a negative ORP. The World Health Organization (WHO) recommends that the ORP of drinking water not exceed 60 mV.
  • Freshly made fruit and vegetable juice have an ORP of around -50 mV.

Other Ways of Creating Diatomic Hydrogen Enriched Water

You can breath molecular hydrogen H2 gas, you can inject molecular hydrogen H2 rich saline or use it as eye drops, you can bathe in it, you can put it on your skin, you can increase the production of molecular hydrogen H2 by intestinal bacteria … OR you can create molecular hydrogen H2-rich water created by an electric  water ionizer or from hydrogen-producing tablets of magnesium .

Which method of producing molecular hydrogen in water is best?

Early research suggests that the most effective – and easiest approach is to drink  molecular hydrogen H2-rich water.

molecular hydrogen  (H2) water can be produced using electrolysis, dissolving tablets or dissolving molecular hydrogen H2 gas into water

Magensium tablets that dissolve in water are a convenient way to produce molecular hydrogen H2 rich water. Using the right form of magnesium mixed with other ingredients, a reaction takes place with water to produce dissolved hydrogen gas.[Mg + 2 H20 >>> H2 + 2OH-]. This is the most common method used by scientific researchers for human and animal studies.

This method can achieve high concentrations of molecular hydrogen that is further enhanced when electrically ionized alkaline water is also used. This method produces by far the highest concentration of molecular hydrogen H2 and is a great way to supplement the usage of clean, alkaline, ionized water taken during the rest of the day.

Magnesium tablets that are taken internally without being dissolved in water may also be effective (one published study) but these tablets are hard to dissolve, even in a buffered acid solution.

It may take several hours to release all the molecular hydrogen gas, and this is similar to molecular hydrogen gas produced by gut bacteria.

ATTENTION! There is on the market a non-electric water ionizer unit that claims to be capable of creating high levels of hydrogen water using water flow through (like an electric water ionizer) but in reality after about a liter of water flows through the production of molecular hydrogen H2 drops dramatically because the magnesium does not have enough time to soak and react with the water.

Follow-up

To discover more about AlkaViva’s hydrogen generating, electric water ionizers please click on following links:

Alkaline ionized water on long & short terms – RULES and WARNINGS of use / consumption & storage / bottling

Alkaline ionized water on long & short terms – RULES and WARNINGS of use / consumption & storage / bottling

How to Use/Drink Alkaline Ionized  Water

The ideal pH level of alkaline ionized water for long term human consumption is between 8.5 and 9.5 (and no greater than 10.0) with the ideal ORP value around -250mV to -350mV (and in no way significantly greater than -400mV).

Warnings :

1. long term consumption of alkaline water with a pH >10

PH values significantly higher than 10 are unfit for human consumption as indicated by the World Health Organization and the Environmental Protection Agency. In fact water with high PH values such as 11 is found in ammonia solution and a PH value of 13 is the PH value found in household bleach!

For more details & uses of higly alkaline ionized water for cleaning & stain removal read this article- clic

For long term drinking of ionized alkaline water, a max of 9.5 pH is a good number but more importantly it is good to get a low –ORP (less than -300 is ideal).  Trouble is that -ORP is not easy to measure and usually the devices used are inaccurate. Also good for most people to start on low level for first few days or until they feel they can easily go up to a higher level.  If someone is very sick and even a low level feels too much then they can always mix low level ionized water with just filtered water from ionizer.
I do not like meat but understand also that some people are helped by having a  diet that also includes meat.  But regardless and in all cases more healthy fruits, vegetables, greens and enough good water are always good.

2. long-term rules/concerns of alkaline ionized water consumption:

Don’t do any alkaline water drinking with meals containing meat or dairy, and watch your body whenever you are introducing a dietary change just for good measure.

Do not drink it while taking medications [natural vitamins are fine though].

In Japan and Korea,  population has been drinking ionized water for over 30 years…some even longer. Many hospitals in both Japan and Korea use water ionizers for both its alkalizing/anti-oxidizing properties for drinking and for its acid properties in healing skin sores. Even high-classed hotels have water ionizers in every room.

15% of the population of Japan that drink ionized alkaline water from water ionizers have a 10 plus year longer life expectancy than those in the United States? And they have been drinking the ionized water for an average of only 12 years! Just think if they would have started drinking ionized water from birth!

In those countries their way of life and healing is more holistic than ours. The undeniable benefits of alkaline ionized water have been experienced over a very long time in both Korea and Japan, and with ever-growing popularity and scientific validation, water ionizers are finally becoming more well-known and used in the US.

Innumerable tests have been done on mice, rats, chickens, etc., and in almost every instance there were good results noted and no negative results have ever been able to be replicated. There have been no substantiated incidents of negative long-term effects of people drinking ionized water.

Read whole article about long term effects of ionized alkaline water -click here

Storing & bottling ionized alkaline water

When you produce alkaline ionized water the antioxidant hydroxyl ions (ORP) are fleeting in nature and will only last a maximum of 18 to 24 hours. For this reason it is best to drink the water immediately upon leaving the machine or within 6 hours time. Bottling or storing the water will not prolong the life of the hydroxyl ions and in fact you should only store what water you will be drinking during that same day. The best container to store your alkaline ionized water in is a dark glass container that is sealed and kept in a cold dark location such as your refrigerator. Exposure to oxygen in the air and light will speed up the process of decay leading to a faster loss of its antioxidant proprieties.

Due to the fleeting nature of the antioxidant hydroxyl ions bottling or storing alkaline ionized water is in no way capable of preserving the therapeutic antioxidant effects of the water. For this reason purchasing bottled alkaline water is not as beneficial as drinking the alkaline ionized water when it is fresh from the machine or in 6 hours time of its creation. Notice that when you purchase bottled water it is called “alkaline water” and not “alkaline ionized water” because of the fact that all of the hydroxyl ions have decayed. The water cannot legally be sold and called “alkaline ionized water” because all of the antioxidant hydroxyl ions have evaporated, it must now be sold strictly as “alkaline water”.

When you purchase “alkaline water” you may still get water with a higher pH (the higher PH value will remain for several months while the ORP value will dissipate completely within 24 hours) but it won’t have the same antioxidant properties as water that is fresh from the machine since the majority if not all of the ORP has evaporated from the water.

To receive the most therapeutic effects from your water ionizer be sure to drink your alkaline ionized water when it is fresh from the machine or within at most 6 hours time. If you have to take the water with you to work or on the road bottle it in a dark glass container and try to keep it sealed while placing it in a dark cold location.

Health benefits of drinking alkaline ionized water viewed by Leading Doctors and researchers

Health benefits of drinking alkaline ionized water viewed by Leading Doctors and researchers .

 

 

  • Ben Johnson M.D.

Doctor of Osteopathy(D.O.),Naturopathic Medical Doctor (N.M.D.) Dr.Johnson was featured on the best selling DVD “TheSecret.”

“As an alternative medical doctor and especially treating cancer,the most important psychological issue was emotions,but the most important physical issue was pH.In 1931, Otto Warburg received the Nobel Prize in Medicine for discovering that a low oxygen environment in the tissues was the cause of cancer. The cause fora low oxygen level intissue is acid pH.

When I learned about alkaline water,I became very excited.We are now able to inundate a person’s body on a very basic level.  Since a body is made up of almost 70 percent water,changing the alkalinity of that water would be a huge accomplishment.

Alkaline antioxidant water changes everything physiologically.  It allows the enzyme systems to work the way they should.The alkalinity allows oxygen to get to the tissues.More importantly,it provides ready antioxidants to keep our bodies from rotting and rusting through the process of oxidation.

The alkaline antioxidant water solves two of the major problems that cause aging and disease:  low pH and free radicals.  It helps you get healthy and stay healthy by the alkalization of the blood and the antioxidant potential or the oxidation reduction potential ( ORP ).

The question is often asked:  Who should be drinking the alkaline antioxidant water?The answer is simply, everyone from children to octogenarians.”

 Ben Johnson M.D. endorses & recommends Jupiter/ AlkaViva water ionizers

  • Robert O. Young Ph.D.,N.D.

In his book“The pH Miracle” Dr. Young says it this way: “Those willing to look again, and with clear eyes,will be rewarded with the secrets to permanent health.We can heal ourselves by changing the environment inside our bodies.Potentially harmful invaders then,will have nowhere to grow and will become harmless.”

High pH water,such as the water that comes from a good water ionizer, neutralizes acids throughout the entire body. Since acids underlie all disease entities, nothing makes more sense than neutralizing these acids.

One of my most often quoted statements goes like this: “When the fish is sick, change the water.   We don’t feed the fish medicine.  We give them clean water.When the cells of our body are sick, we must change the water and fluids in which all cells and tissues are bathed.”

I can’t think of any investment that is better for a person or a family than a good water ionizer.

  

  

Robert O. YoungPh.D.,N.D.  endorses & recommends Jupiter/ AlkaViva water ionizers

  • Theodore BaroodyD.C.,N.D.,Ph.D.,Dipl.Acu

Author of the book“Alkalize or Die”

“I have administered over 5000 gallons of this water for about every health situation imaginable.I feel that restructured alkaline water can benefit everyone.”The countless names attached to illness do not really matter. What does matter is that they all come from the same root cause:  too much tissue acid waste in the body.”

  Theodore BaroodyD.C.,N.D.,Ph.D.,Dipl.Acu  endorses & recommends Jupiter/ AlkaViva water ionizers

  • Hidemitsu Hayashi M.D. HeartSurgeon, Director of the Water Institute ofJapan

Dr. Hayashi believes that ionized water is our best source of antioxidants.   “There is no substitute for a healthy balanced diet, especially rich in antioxidant materials such as vitamin C,vitamin E, beta-carotene, and other foods that are good for us.  However, these substances are not the best source of free electrons that can block the oxidation of healthy tissue by active oxygen.  Water treated by electrolysis to increase its reduction potential is the best solution to the problem of providing a safe source of free electrons to block the oxidation of normal tissue by free oxygen radicals.  We believe that reduced water,water with an excess of free electrons to donate to active oxygen, is the best solution because the reduction potential of water can be dramatically increased over other antioxidants in food or vitamin supplements and the molecule weight of reduced water is low.”

 “Alkaline living water is regarded by a growing number of health care professionals as the best water to drink and is listed as a medical device in Japan for the treatment of degenerative diseases.”

 

  • Ray Kurzweil Ph.D.

Well renowned author  & inventor.  Dr. Kurzweil has received twelve honorary Doctorates and honors from three U.S. presidents.

kurzweil1

 

“The most important feature of alkaline water produced by a water alkalinizer is its oxidation reduction potential (ORP).Water with a high negative ORP is of particular value in its ability to neutralize oxygen free radicals.ORP can alsobe directly testedusingan ORP sensor and meter.  We have conducted these experiments as well.  We found that water coming directly from the tap had an ORP of +290mV, while the water coming out of the water alkalinizer had a negative ORP.The more negative the ORP of a substance(that is, the higher its negative ORP),the more likely it is to engage in chemical reactions that donate electrons.  These electrons are immediately available to engage in reactions that neutralize positively charged free radicals.This is the key benefit of water produced byawater alkalinizer that is not available by simply drinking water that has had some bicarb or other compounds dissolved in it to make it alkaline.”

  • Prof. Kuninaka Hironaga, Head of Kuninaka-Hospital, Japan

“Mr. Yamada, the head of Police Research Institute, suffered from severe allergy. He was treated repeatedly by skin specialist, but with no success. Then he started consuming ionized water. The allergyresponded very well and was soon completely cured. No relapse had occurred, although he had taken all kinds of food. He was most grateful and excited about this treatment.

As for myself, I had also suffered severe allergy. Ever since I began to consume ionized water, the  allergy  has  recovered.  Since then,  I started a research on the effectiveness of ionized water.

I discovered that most allergies is due to acidification of body condition and is also related to consuming too much meat and sugar. In every allergy case, the patient’s antioxidant minerals are excessively low which in turn lower the body resistance significantly. The body becomes overly sensitive and develops allergy easily. To stabilize the sensitivity,  calcium solution  is injected into the vein. Therefore, it is clear that the ionized water has ionic calcium, which can help alleviate allergy.

The ionic calcium not only enhances the heart, urination, and neutralization of toxins but controls acidity. It also enhances the digestive system and liver function. This will promote natural healing power and henceincrease its resistance to allergy. In some special cases of illness, which do not respond to drugs, it is found, it is found to respond well to ionized water.”

  • Prof. Kuninaka Hironage, Head of Kuninaka Hospital

“Too many fats in the diets, which lead to the deposition of cholesterol on the blood vessels, which in turn constrict the blood flow, cause most illnesses such as high blood pressure. In accordance with thetheory of Professor Gato of Kyushu University on Vitamin K (because vitamin K enables the blood calcium to increase), or the

consumption of more antioxidant water, the effectiveness of the increase in the calcium in high blood pressure is most significant. The consumption of alkaline antioxidant water

for a period of 2 to 3 months, I have observed the blood pressure slowly drop, due to the water’s solvent ability, which dissolves the cholesterol in the blood vessels.”

 

  • Prof. Kuwata Keijiroo, Doctor of Medicine, Japan

“In my opinion, the wonder of ionized water is the  ability neutralizes toxins, but it is not a medicine.  The difference is that the medicine can only apply to each and individual case. Whereas the ionized water can be consumed  generally and it’s neutralizing power is something which is very much unexpected. Now, in brief, let me introduce to you a heart disease case and how it was cured.

The patient was a 35 years old male suffering from vascular heart disease. For 5 years, his sickness deteriorated. He was in the Setagays Government Hospital for treatment.

During those 5 years, he had been in and out of the hospital 5 to 6 times. He had undergone high tech examinations such as angiogram by injecting VINYL via the vein into the heart. He consulted and soughttreatment from many good doctors where later he underwent a major surgical operation. Upon his discharge from the hospital, he quit his job to convalesce. However, each time when his illness relapsed, theattack seemed to be even more severe. Last year, in August, his relatives were in despair and expected he would not live much longer. It so happened at that time that the victim’s relative came across ionized water processor. His illness responded well and he is now on the road to recovery.”

Note: In the United States, cardiovascular diseases account for more than one-half of the approximate 2 million deaths occurring each year. It is estimated that optimal conditioning of drinking water could reduce this cardiovascular disease mortality rate by as much as 15 percent in the United States.

From: Report of the Safe Drinking Water committee of the National Academy of Sciences, 1977

 

  •  Prof. Kuninaka Hironage, Head of Kuninaka Hospital

“For over 10 years of my experience, my concept toward minerals, especially pertaining to ionic calcium in high blood pressure and other diseases is most significant.

In accordance to the theory of medical Professor Gato of Kyushu University on Vitamin K (because vitamin K enables the blood calcium to increase), or the consumption of more ionized water, the effectiveness of the increase in the calcium in high blood pressure is most significant. Too many fats in the diets, which lead to the deposition of cholesterol  on the blood vessels, which in turn constrict the blood flow, cause most illnesses such as high blood pressure.

By drinking ionized water for a period of 2 to 3 months, the blood pressure should slowly drop, because the ionized water is a good solvent, which dissolves the cholesterol in the blood vessels.”

  • David S. Dyer N.M.D.,Ph.D.

“Restructured alkaline water may well be the best element or supplement you can put in your body!Did you know the Japanese have researched this subject for over forty years and have found that drinking restructured alkaline water can relieve or reduce the three main causes for sickness,disease and pre‐mature aging?

Restructured alkaline water made using electrolysis has been consumed by the Japanese for over 40 years and has touched and changed every disease and condition imaginable.  I have been using this water for over 6 years and have seen similar results when it is used persistently and consistently.The water is smooth, delicious,hydrating, energizing, permeating,pH balancing and a strong antioxidant.Does this sound like the water you should be drinking?I wish you all good health.. .”

 

  • Fereydoon Batmanghelidj M.D.

“I am a researcher.  I have researched dehydration for the past 20 years. When I discovered that the solution to most of the disease conditions of our society is not a money maker,I decided to take my information to the public.My research revealed that unintentional dehydration produces stress, chronic pains and many degenerative diseases. Dry mouth is not the only sign of dehydration and waiting to get thirsty is wrong.Medicine has based its understanding that it is solid matter in the body that regulates all functions of the body. I have explained scientifically at the molecular level that it is water that regulates all functions of the body including functions of solid matter.75 % of our bodies are composed of water.The brain is 85% water.  It is water that energizes and activates the solid matter.  If you don’t take enough water, some functions of the body will suffer. Dehydration produces system disturbances.When I use the words water cure,I am referring to curing dehydration with water.”

His message to the world is:  “You are not sick, you are thirsty; don’t treat thirst with medication.”His ground‐ breaking book, “Your Body’s Many Cries for Water”, has been translated into 15 languages and has sold over a million copies.

 

  • Henri Coanda the Romanian father of fluid dynamics and a Nobel Prize winner at 78 yrs old,spent six decades studying the Hunza water trying to determine what it was in this water that caused such beneficial effects for the body.He discovered that it had a different viscosity and surface tension.

Dr.Patrick Flanagan and others continued the research.  They found Hunza water had a high alkaline pH and an extraordinary amount of active hydrogen (hydrogen with an extra electron), with a negative Redox Potential and a  high colloidal mineral content.

Similar natural water properties and longevity are found in other remote unpolluted places such as the Shin‐Chan areas of China, the Caucasus in Azerbaijan, and in the Andes Mountains.

There are five locations in the world where scientists have found a type drinking water that exhibits extraordinary physical characteristics and where the inhabitants reportedly live to be over 100 years of age, are in excellent health, have no cancer, no dental caries, are robust and have children in their old age. They are called Hunzaland in the Karkorum Mountains just north of Pakistan in the Himalayas, the Vilcambamba in Ecuador, a high mountain valley in Georgia, Russia, another in Mongolia and the final one in Peru.  Though all these areas have different cultures and diets, they all have one thing in common – their water has similar properties.We studied them & tried our best to replicate them!

If interested, please ask for our FREE DVD on this trip contact us or leave your mail address( we will not share it with anyone)  [contact-form subject=’Valley DVD’][contact-field label=’Email’ type=’email’ required=’1’/][contact-field label=’Comments’ type=’textarea’/][/contact-form]

 

In efforts to recreate the Hunza water, Japanese scientists investigated Russian electrolysis technology.They found that electricity could be used to re‐ structure the water,giving it properties similar to Hunza water.

 

This functional water technology was first developed in Japan in the early 1950’s and the experiments were first conducted on plants and animals.

Full scale development started in 1954 by several agricultural universities on the effects of ionic water,especially acid water,on plants; experiments by Japanese doctors followed, using alkaline ionized water on their patients.

The first ionizers were large units used in hospitals.

Following efforts by Japanese medical doctors,the water ionizer was approved for medical therapeutics by the Japanese Ministry of Health and Rehabilitation in January 1966. Later they were also approved as medical devices by the government of South Korea.

Some 30 million people in Japan have used a water ionizer over the last 40 years.

 

  • Sherry Rogers M.D.

Dr. Sherry Rogers is a medical doctor in private practice for over a quarter of a century.Her specialty is finding the cause of illness and getting rid of symptoms that are undiagnosable. Dr. Rogers has written books, scientific papers,and taught advanced courses to physicians learning these techniques. She has lectured in six countries and over fifty U.S.cities, and has been interviewed on dozens of television shows and radio programs, as well as having written numerous magazine articles.”No longer is a headache a Darvon deficiency.We now have the tools with which any symptom can be turned around,including many cancers,chemical sensitivity, allergies,and much more. “Alkaline water rids the body of acid waste…After carefully evaluating the results of my advice to hundreds of individuals,I’m convinced that toxicity in the form of acidic waste is the primary cause of degenerative disease.”

 

  • Susan Lark M.D.

 

Dr. Susan Lark, university lecturer and author of “The Chemistry of Success”,says: Drinking four to six glasses of alkaline water a day will help to neutralize over‐acidity and over time will help to restore your buffering ability.  Alkaline water should be used when conditions of over‐acidity develop,such as cold,flu or bronchitis.  Like vitamins C, E and Beta Carotene,alkaline water acts as an antioxidant because of its excess supply of free electrons.  This can help the body against the development of heart disease,strokes, immune dysfunctions, and other common ailments.”

 

  •  Prof. Hatori Tasutaroo, Head of Akajiuiji Blood Centre, Yokohama Hospital, Faitama District: “Due to a higher standard of living, our eating habits have changed. We consume too much proteins, fats and sugar. The excess fats   and carbohydrates  are in the body as fats.

In the present lifestyles, Americans are more extravagant about food compared to the Japanese. Due to this excessive intake  obesity is a significant problem. Normally, one out of five males and one out of fourfemales are obese.

The degree of “burn-out” in food intake largely depends on the amount on intake of vitamins and minerals.  When excessive intake of proteins, carbohydrates and fats occurs, the requirement for vitamins and minerals increases. However, there is not much research carried out pertaining to the importance of vitamins and minerals.

Nowadays, many people suffer from acidification that leads to diabetes, heart diseases, cancer, liver and kidney diseases. If our food intake can be completely burned off, then there is no deposition of fats. Obviously, there will be no acidification problem and hence there should not be any sign of obesity.

The ionized water contains an abundance of ionic calcium. This ionic calcium helps in the “burn-off” process. By drinking ionized water, it provides sufficient minerals for our body. As a result, we do not need to watch our diet to stay slim.

Hence, ionized water is a savior for those differing from obesity and many adult diseases, providing good assistance in enhancing blood health.”

  • Helmut G.Flasch M.D.

The “very clean waters”produced by reverse osmosis (which also issused by most bottled water companies) is called”hungry”or “death” water.It is so clean that nothing is left in it. The water is charged with positive ions instead of negative ions and is also acidic instead of alkaline.  The water you drink is supposed to bring all nutrients to the destination and to flush out any free radicals.   The only acidic are as in your body should be the stomach and the urine! Keeping your body alkaline, not acidic, is the answer.  Having an alkaline body is the ultimate,most underlying answer,according to some of the most respected brains on this planet.All ways of living should be geared towards achieving an alkaline body!

  • Keiichi Morishita M.D.,Ph.D.

in his book “The Hidden Truth of Cancer”says:

“If the blood develops a more acidic condition,then these excess acidic wastes have to be deposited somewhere in the body.If this un healthy process continues year after year, these areas steadily increase in acidity and their cells begin to die. Other cells in the affected area may survive by becoming abnormal; these are called malignant. Malignant cells cannot respond to brain commands.  They undergo a c ellular division that is out of control.  This isthe beginning of cancer.”

“Modern medicine.. treats these malignant cells as if they were bacteria and viruses, it uses chemotherapy, radiation and surgery to treat cancer.  Yet none of these treatments will help very much,if the environment of the body continues to remain acidic.”

 

Prof. Kuwata Keijiroo, Doctor of Medicine, Japan

 

“When I was serving in the Fire Insurance Association, I used to examine many diabetic patients. Besides treating them with drugs, I provided them with ionized water. After drinking ionized water for one month, 15 diabetic patients were selected and sent to Tokyo University for further test and observations.

Initially, the more serious patients were a bit  apprehensive  about the treatment. When the ionized water was consumed for some time, the sugar in the blood and urine ranged from a ratio of 300 mg/l to 2 mg/ dc.There was a time where the patient had undergone 5 to 6 blood tests a day and detected to be within normal range. Results also showed that even 1 1/2 hour after meals, the blood sugar and urine ratio was 100 mg/dc 0 mg/dc. The sugar in the urine has completely disappeared.”

 

  • Harald Tietze

Harald Tietze, author of Youthingsays that”by drinking alkaline water, the aging process can be reversed and the wastes can be reduced in the long‐term to a level of a much younger person.  The functions of the organs can be revived.”

 

  • Ingfreid Hobert M.D.

 

“You do not need expensive medicine with all the negative side effects to regain health… Alkaline water has profound long term effects because it alkalizes your body and provides an effective antioxidant.”

  • Prof. Kogure Keizou, Kogure Clinic of Juntendo Hospital, Japan

“The stomach is readily upset both by diseases affecting the stomach and by other general illnesses. In addition, any nervous tension or anxiety frequently causes gastric upset, vague symptoms when they are under some strain.

The important role of ionized water in our stomach is to neutralize the secretion and strengthen it s functions. Usually, after consuming the ionized water for 1 to 3 minutes, the gastric juices increase 1 1/2 times. For those suffering from  hyperchlorhydria  (excess stomach acid) or achlorhydria  (low in stomach acid) the presence of ionized water will stimulate the stomach cells to secrete more gastric juice. This in turnenhances digestion and absorption of minerals.

However, on the other hand, those with hyperchlorhydria (excess stomach acid) the ionized water neutralizes the excessive gastric juice. Hence, it does not create any adverse reaction.

According to the medical lecturer form Maeba University, the pH of the gastric secretion will still remain normal when ionized water is consumed. This proves that the ability of the ionized water is able to neutralize as well as to stimulate the secretion.”

 

  •  Arthur M. Ecano M.D.

Dr. Ecano says that”if the world has accepted antioxidants to slow down the aging process,it should readily agree to the uses of ionized alkaline water as an anti‐aging agent.Their roles are closely linked and intertwined such that a lasting anti‐aging program is incomplete without addressing both free radicals and organic acid wastes.”

 

  • Prof. Watanabe Ifao. Watanabe Hospital, Japan

“Ionized water improves body constituents and ensures effective healing to many illnesses. The uses of ionized water in gynecological patients have proved to be very effective. The main reason for its effectiveness is that this water can neutralize toxins.

When given ionized to pre-eclamptic toxemia cases, the results are very significant. During my long years of servicing the pre-eclamptic toxemia cases, I found that the women with pre-eclamptic toxemia who consumed ionized water tend to deliver healthier babies with stronger muscles. A survey report carried out on babies in this group has intelligence above average.”

  •  Prof. Tamura Tatsuji, Keifuku Rehabilitation Center, Japan

“Eczema is used to describe several varieties of skin conditions, which have a number of common features. The exact cause or causes of eczema are not fully understood. In many cases, eczema can be attributedby external irritants.

Let me introduce a patient who recovered from skin disease after consuming the ionized water. This patient suffered 10 years of eczema and could not be cured effectively even under specialist treatment. This patient, who is 70 years of age, is the President of a vehicle spare parts company. After the war, his lower limbs suffer acute eczema, which later became chronic. He was repeatedly treated in a specialist skin hospital.

The left limb responded well to treatment, but not so on the right limb. He suffered severe itchiness, which, when scratched led to bleeding. During the last 10 years, he was seen and treated by many doctors. When I first examined him, his lower limb around the joints was covered with  vesicles. Weeping occurred owing to serum exuding from the vesicles.

I advised him to try consuming ionized water. He bought a unit and consumed the ionized water religiously and used the acidic water to bathe the affected areas. After 2 weeks of treatment the vesicles dried up. The eczema was completely cleared without any relapse after 1 1/2 month.”

  • Prof. Kuwata Keijiroo, Doctor of Medicine, Japan

 

Dr Kerijiroo explains that for severe kidney failure, water intake has to be restricted. However whereas ordinary tap water “contains phosphate, calcium carbonate and the acidic ions. . . . [that] tend to reducethe efficiency of the calcium ions. . . .” he feels that in controlled amounts, Alkaline Ionic water will “strengthen the heart and increase urination.

He goes on to claim that over the next six to twelve months, the patient should maintain an alkaline diet (reduced animal protein)  and continue drinking  the Alkaline Ionic water to reduce the amounts of urea and uric acid in the blood. He also feels that, through his clinical experience that patients undergoing kidney dialysis should also drink Alkaline Ionic water as well as those patients with kidney disease who do not respond to drugs.

water ionizer working principle : alkaline ionized water – what is it? And what is water ionizer pH & H2?

water ionizer working principle : alkaline ionized water – what is it? And what is water ionizer pH & hydrogen H2?
What are a water ionizer (health) benefits ?

water ionizer – how does it work?

AlkaViva water ionizers& purifiers
AlkaViva water ionizers& purifiers

water ionizer defined /  definition:

The water ionizer unit, about the size of a bread maker, is an electronic water filter connected to your (kitchen) water supply to perform controlled low voltage electrolysis /ionization  on input (tap) water before you drink it or use it in the kitchen for cooking or cleaning.

After water ionizer installation a special attachment redirects input (tap) water out of the faucet through a plastic water ionizer hose into the water ionizer purifier and alkalizer machine .

A water ionizer purifier and alkalizer machine usually has 2 key parts:

1 . first a water ionizer filtration system (1 or 2 water ionizer filters) that cleans the tap water or water you put into your water ionizer purifier unit

2. second a ‘ water ionizer alkalizer ‘system composed composed from a water ionizer chamber ( here is where the water ionizer platinum plates /electrodes are located and water electrolysis / ionization /takes places hydrogen gas is generated more or less depending on  water ionizer chamber membranes)  controlled by a electronic water ionizer circuit board/ ‘ a dedicated microcomputer, to ensure the exact result time after time.’ – this electronic part takes your alkaline/ purified /  acidic water commands and tells the water ionizer chamber what to to with the filtered water that enters it  .

By water electrolysis the input filtered water (that enters the water ionizer chamber and comes in contact with the water ionizer platinum plates ) is split into 2 output streams :

  1.  ionized alkaline water that is also antioxidant due to molecular hydrogen gas dissolved in it via electrolysis ( a water ionizer is a generator of hydrogen in water ) and has many clinically proven benefits in various health conditions –  a lot of science , research , studies on this topic( usually water ionizer health benefits range from cancer , diabetes , pressure ulcers, weights loss , sports to ionized water  for kidney disease / kidney failure / dialysis and  much more – alkaline ionized water is good for you  )  – we think clinically proven alkaline ionized hydrogen water benefits are more objective than testimonials or consumer reports  this alkaline ionized water is for drinking (pH <10)  . Does alkaline ionized water from ionizer have any side effects / negative effects ? If the water ionizer pH is lower than 10 there are no water ionizer health risks that we are aware of so far (please read the link above hydrogen water safety – you will also find answers regarding water ionizer benefits,water ionizer research, water ionizer study etc ) . If the water ionizer pH is above 10 please do not drink this ionized alkaline water (at least not for a very long time ; rather use this highly alkaline ionized water for cleaning you laundry / washing machine ,  fruits, vegetables and cooking- ionized water how to – click)

 2 . acid(pH<7) ionized water that is oxidative and is usually used externally for disinfecting wounds, skin, eczema or surfaces as strongly acid ionized water kills bacteria : you can use acid ionized water to rinse hair , clean windows and other surfaces ; for more details about acid ionized water home use -acidic ionized water how to- click

 

The reduced alkaline ionized water (antioxidant hydrogen water) comes out of the faucet, and the oxidized acid water comes out of a separate water ionizer hose leading into the sink. You can use the reduced water for drinking or cooking.

We drink the alkaline ionized water and we apply the acid ionized water externally (did you know that water ionizers were used in Japan for acid ionized water disinfection before becoming aware of the rest of health benefits ) . How simple and how wonderful! I hope I have answered some of your questions regarding things like ‘is a water ionizer good or bad’, what are a water ionizer health benefits /  water ionizer health risks / negative effects? water ionizer home use , ionized water truth or fiction ? in case I didn’t please read below

‘water ionizer nutrition facts’:

 water ionizer pH 

The pH scale ranges from 0 on the acidic side to 14 on the alkaline, and a solution is neutral if its pH is 7.

At pH 7, water contains equal concentrations of H+ and OH- ions. Substances with a pH less than 7 are acidic because they contain a higher concentration of H+ ions.
The pH scale is a logarithmic scale, so a change of one pH unit implies a tenfold shift in the concentration of hydrogen ions.

pH 6 means you are ten times more acid than pH 7.

pH 5 means you are a hundred times more acid than pH 7

The Importance of Balancing pH

pH ScaleLiving things, including humans, are extremely sensitive to pH.
Blood plasma and other fluids that surround the cells in the body have a pH of 7.2 to 7.45.

A blood pH of 6.9 can induce coma and death. That is why all bodily systems are secondary in importance to the system of pH balancing. Your body will willingly shut down digestion, alter temperature, rob your bones of calcium, deprive your pancreas, just to maintain adequate fluid buffers of alkalinity to balance the `acid tide` we inflict upon ourselves through diet and stress etc.

However your body possesses numerous special mechanisms to aid in stabilizing these fluids so that cells will not be subject to appreciable fluctuations in pH.

Substances which serve as mechanisms to stabilize pH are called BUFFERS.

Buffers have the capacity to bond ions and remove them from solution whenever their concentration begins to rise. Conversely, buffers can release ions whenever their concentration begins to fall, thus helping to minimize the fluctuations in pH. This is an important function because many biochemical reactions normally occurring in living organisms either release or use up ions.

Imagine now what a load is taken off your body if its primary safety system of pH balancing can be `stood down` from a continual `full alert` because you now are alkalizing your body through reducing stress, eating healthier foods, avoiding harmful chemicals and drinking adequate amounts of clean, healthy ionized alkaline water!

Alkaline ionized water restores the body’s pH balance

PEER REVIEWED ARTICLES ON ALKALINE DIET BENEFITS FROM INCREASING ALKALINITY IN THE BODY

Alkaline ionized water includes a powerful antioxidant – molecular hydrogen

Alkaline ionized water is a strong source of anti-oxidants since it contains an abundance of free electrons which can be donated to the body in order to neutralize free radicals.

But what exactly is oxidation? Think of what happens to a slice of apple left out on the counter for a few hours: it turns brown due to exposure to unstable oxygen molecules in the air.  Inside our bodies, our cells are also continuously subjected to oxidation due to the presence of oxygen free radicals, which are unstable molecules desperately seeking electrons for stability.  Free radicals have been scientifically proven to cause cellular and DNA damage that contribute to aging and can lead to the onset of various diseases.

 

MOLECULAR HYDROGEN

Alkaline ionized water(AIO) or Electrolisys Reduced Water (ERW) is most efficiently produced by using an electric water ionizer & alkalizer . Alkaline ionized water (also molecular hydrogen water) is marketed by many names. Until recently this water was commonly referred to scientifically as Electrolyzed Reduced Water (ERW).

Now, scientists are often referring to it as Molecular Hydrogen Water. This is because research (especially in the past 10 years) has shown that the dissolved molecular hydrogen gas (H2), present in water created by electric water ionizers, is what is mainly responsible for its many benefits. Perhaps the most accurate name is electrolytically-produced, hydrogen-enriched, alkaline water.

Why  molecular hydrogen H2 (water)
is good for  your health regimen?

H2 molecular hydrogen (water) is the Master Antioxidant
Molecular hydrogen is the smallest element and lightest molecule so it easily diffuses into subcellular compartments scavenging dangerous oxygen radicals and so protects DNA and RNA from oxidative stress.

H2  Molecular hydrogen  Activates your Body’s own Powerful Enzymes
Molecular hydrogen H2 triggers the activation of additional antioxidant enzymes such as glutathione and other cell-protective proteins.

Research Suggests Therapeutic Benefit of Molecular hydrogen in Over 130 Disease Models
Over 1000 peer-reviewed scientific articles indicate this fact. Drinking H2-Molecular hydrogen saturated water produced the vast majority of the benefits observed.

H2 Molecular hydrogen Can Favorably Alter Cell Metabolism, Signaling and Gene Expression 
Research suggests that Molecular hydrogen H2 could improve cell signaling functions and provide anti-inflammatory, anti-allergic and anti-apoptotic (anti-cell death) effects.

The Benefits of Molecular hydrogen (water)

Due to the large amount of research, over the past ten years, on the effects of Molecular hydrogen H2 in water, we now know that the hydroxide ion (OH-) is NOT responsible for most of the positive effects observed when drinking alkaline ionized water. The active antioxidant in ionized water is dissolved molecular hydrogen (H2).

In 2010, a review article, published in “Free Radical Research” stated; “It is not an overestimate to say that hydrogen’s impact on therapeutic and preventative medicine could be enormous in the future”. Since that article was published there have been over 200 peer-reviewed articles published, that focus on about 80 different diseases models, and that conclude that molecular hydrogen (water) appears to have a beneficial effect.